9-(2-Hydroxypropyl)adenine-13C5

CAS: 14047-26-8

Ref. TR-H952012

Informação sobre produto

• Nome: 9-(2-Hydroxypropyl)adenine-13C5
• Sinónimos: 6-Amino-α-methyl-9H-purine-9-ethanol-13C5, (RS)-9-(2-Hydroxypropyl)adenine-13C5, 9-(2-Hydroxyprop-1-yl)adenine-13C5, DL-9-(2-Hydroxypropyl)adenine13C5, DL-6-amino-α-methyl-9H-Purine-9-ethanol-13C5, (±)-6-amino-α-methyl-9H-Purine-9-ethanol-13C5
• Marca: TRC
• Descrição: Applications 9-(2-Hydroxypropyl)adenine-13C5 is an intermediate used in the synthesis of rac Tenofovir-13C5 (>90%) (T018501), which is he isotope labelled analog of Tenofovir (T018500); an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor. Also used as an anti-HIV agent and antiviral.References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997); Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005); Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006); Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007)

Propriedades químicas

• Peso molecular: 198.169
• Fórmula: C₅C₃H₁₁N₅O
• Cor/forma: Neat
• InChI: InChI=1S/C8H11N5O/c1-5(14)2-13-4-12-6-7(9)10-3-11-8(6)13/h3-5,14H,2H2,1H3,(H2,9,10,11)/i3+1,4+1,6+1,7+1,8+1
• Chave InChI: InChIKey=MJZYTEBKXLVLMY-XQLHBIPJSA-N
• SMILES: CC(O)Cn1[13cH]n[13c]2[13c](N)n[13cH]n[13c]21