2-[(2-Hydroxy-4,5-dimethoxybenzoyl)amino]-4-thiazolecarboxylic Acid (>90%)

CAS: 1809272-85-2

Ref. TR-H972788

Informação sobre produto

• Nome: 2-[(2-Hydroxy-4,5-dimethoxybenzoyl)amino]-4-thiazolecarboxylic Acid (>90%)
• Sinónimos: 4-Thiazolecarboxylic acid, 2-[(2-hydroxy-4,5-dimethoxybenzoyl)amino]- (ACI), 2-[(2-Hydroxy-4,5-dimethoxybenzoyl)amino]-4-thiazolecarboxylic acid (ACI), 2-(2-Hydroxy-4,5-dimethoxybenzamido)thiazole-4-carboxylic Acid, 2-(2-Hydroxy-4,5-dimethoxybenzamido)-1,3-thiazole-4carboxylic Acid
• CAS: 1809272-85-2

Descrição

Applications 2-[(2-Hydroxy-4,5-dimethoxybenzoyl)amino]-4-thiazolecarboxylic Acid is an impurity of Acotiamide (A190260), an acetylcholinesterase inhibitor which has been shown to stimulate gastric motility and improve gastric motility dysfunction in rats. Acotiamide Hydrochloride has also been shown to improve meal-related symptoms of functional dyspepsia.
References Masanao, K., et. al.: Eur. J. Pharmacol., 666, 218 (2011); Matsunaga, Y., et. al.: J. Pharmacol. Exp. Ther., 336, 791 (2011)

• Marca: TRC

Propriedades químicas

• Peso molecular: 324.31
• Fórmula: C₁₃H₁₂N₂O₆S
• Pureza: >90%
• Cor/forma: Neat
• InChI: InChI=1S/C13H12N2O6S/c1-20-9-3-6(8(16)4-10(9)21-2)11(17)15-13-14-7(5-22-13)12(18)19/h3-5,16H,1-2H3,(H,18,19)(H,14,15,17)
• Chave InChI: InChIKey=JVFCMPKBFPIOON-UHFFFAOYSA-N
• SMILES: CC(C)c1c(C(=O)Nc2ccccc2)c(-c2ccccc2)c(-c2ccc(F)cc2)n1CCC(O)CC(=O)CC(=O)O