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N-[3-(1H-Imidazol-1-yl)-5-(trifluoromethyl)phenyl]-4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]Benzamide
CAS: 2119583-26-3
Ref. TR-I355005
| 5mg | Descontinuado | ||
| 25mg | Descontinuado | ||
| 50mg | Descontinuado |
Informação sobre produto
Nome:
N-[3-(1H-Imidazol-1-yl)-5-(trifluoromethyl)phenyl]-4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]Benzamide
Sinónimos:
- Desmethylimidazole Nilotinib
- Benzamide
- N-[3-(1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-
- N-[3-(1H-Imidazol-1-yl)-5-(trifluoromethyl)phenyl]-4-methyl-3-[[4-(pyridin-3-yl)pyrimidin-2-yl]amino]benzamide
- Desmethyl Nilotinib
- Desmethylnilotinib
Descrição:
Applications N-[3-(1H-Imidazol-1-yl)-5-(trifluoromethyl)phenyl]-4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]Benzamide, is an imurtiy of Nilotinib (N465300), that might be useful in treatment of chronic myelogenous leukemia.
References Corbin, A., et al.: J. Biol. Chem., 277, 32214(2002), Golemovic, M., et al.: Clin. Cancer Res., 11, 4941 (2005), Gleixner, K., et al.: Blood, 107, 752 (2006), Nicolini, F., et al.: Leukemia, 20, 1061 (2006),
Aviso:
Os nossos productos estão destinados exclusivamente para uso em laboratório. Para qualquer outra aplicação, por favor entre em contacto.
Marca:
TRC
Armazenamento a longo prazo:
Notas:
Propriedades químicas
Peso molecular:
515.49
Fórmula:
C27H20F3N7O
Cor/forma:
Pale Yellow to Pale Beige Solid
InChI:
InChI=1S/C27H20F3N7O/c1-17-4-5-18(11-24(17)36-26-33-8-6-23(35-26)19-3-2-7-31-15-19)25(38)34-21-12-20(27(28,29)30)13-22(14-21)37-10-9-32-16-37/h2-16H,1H3,(H,34,38)(H,33,35,36)
Chave InChI:
InChIKey=WPFXDYJRTVFSEV-UHFFFAOYSA-N
SMILES:
Cc1ccc(C(=O)Nc2cc(-n3ccnc3)cc(C(F)(F)F)c2)cc1Nc1nccc(-c2cccnc2)n1
MDL:
Ponto de fusão:
Ponto de ebulição:
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EINECS:
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Código HS:
