2-Iodo Adenosine35109-88-7

CAS: 35109-88-7

Ref. TR-I686000

Informação sobre produto

• Nome: 2-Iodo Adenosine35109-88-7
• Sinónimos: (2R,3R,4S,5R)-2-(6-amino-2-iodopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol, Adenosine, 2-iodo-

Descrição

Applications An intermediate in the synthesis of isoguanosine (crotonoside or 2-hydroxyadenosine), a naturally occuring nucleoside analogue of guanosine. Isoguanosine is incorporated into mammalian but not bacterial nucleic acids, stimulates the accumulation of cyclic AMP in the brain, and is an inhibitor of IMP:pyrophosphorylase.
References Lowry, B.A., et al.: J. Biol. Chem., 197, 591 (1952), Huang, M., et al.: J. Med. Chem., 15, 462 (1972), Hagen, C., et al.: Biochem. Biophys. Acta, 293, 105 (1973),

• Marca: TRC

Propriedades químicas

• Peso molecular: 393.14
• Fórmula: C₁₀H₁₂IN₅O₄
• Cor/forma: Neat
• InChI: InChI=1S/C10H12IN5O4/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,14,15)/t3-,5-,6-,9-/m1/s1
• Chave InChI: InChIKey=MGEBVSZZNFOIRB-UUOKFMHZSA-N
• SMILES: Nc1nc(I)nc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O