Ivacaftor

CAS: 873054-44-5

Ref. TR-I940600

Informação sobre produto

• Nome: Ivacaftor
• Sinónimos: 3-Quinolinecarboxamide, N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxo-, N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide, Kalydeco, N-(2,4-Di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide, N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide, VX 770, 3-Quinolinecarboxamide, N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxo-, N-[2,4-Bis(tert-butyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide, N-[2,4-Di(tert-butyl)-5-hydroxyphenyl]-4-oxo-1H,4H-quinoline-3-carboxamide, Vx-770
• CAS: 873054-44-5

Descrição

Applications Ivacaftor is used in the treatment of cystic fibrosis.
References Clancy, J. et al.: Am. J. Resp. Crit. Care. Med., 186, 593 (2012);

• Marca: TRC

Propriedades químicas

• Peso molecular: 392.49
• Fórmula: C₂₄H₂₈N₂O₃
• Cor/forma: Off-White
• InChI: InChI=1S/C24H28N2O3/c1-23(2,3)16-11-17(24(4,5)6)20(27)12-19(16)26-22(29)15-13-25-18-10-8-7-9-14(18)21(15)28/h7-13,27H,1-6H3,(H,25,28)(H,26,29)
• Chave InChI: InChIKey=PURKAOJPTOLRMP-UHFFFAOYSA-N
• SMILES: CC(C)(C)c1cc(C(C)(C)C)c(NC(=O)c2c[nH]c3ccccc3c2=O)cc1O