2'-O-Butyryladenosine 3',5'-cyclic phosphate DMAP

CAS: 15392-98-0, 61784-04-1

Ref. TR-K591805

Informação sobre produto

• Nome: 2'-O-Butyryladenosine 3',5'-cyclic phosphate DMAP
• Sinónimos: (4aR,6R,7R,7aR)-6-(6-Amino-9H-purin-9-yl)-2-hydroxy-2-oxidotetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-yl butyrate compound with N,N-Dimethylpyridin-4-Amine (1:1)
• Marca: TRC
• Descrição: Applications 2'-O-Butyryladenosine 3',5'-cyclic phosphate DMAP is an intermediate in the synthesis of 2'-O-Monobutyryladenosine-3', 5'-cyclic Monophosphate (M525120), which is an impurity of Bucladesine Sodium Salt (B689320), a cell-permeable cAMP analogue that activates cAMP dependent protein kinase (PKA) or the cAMP/PKA signaling pathway.References Yamauchi, J., et al.: J. Neurosci., 31, 12579 (2011); Ma, D., et al.: Mol. Pharmacol., 55, 50 (1999)

Propriedades químicas

• Peso molecular: 521.47
• Fórmula: C₁₄H₁₈N₅O₇P·C₇H₁₀N₂
• Cor/forma: Neat
• InChI: InChI=1S/C14H18N5O7P.C7H10N2/c1-2-3-8(20)25-11-10-7(4-23-27(21,22)26-10)24-14(11)19-6-18-9-12(15)16-5-17-13(9)19;1-9(2)7-3-5-8-6-4-7/h5-7,10-11,14H,2-4H2,1H3,(H,21,22)(H2,15,16,17);3-6H,1-2H3/t7-,10-,11-,14-;/m1./s1
• Chave InChI: InChIKey=UXCZYLISTOLTLT-HOLUKZPASA-N
• SMILES: CCCC(=O)O[C@@H]1[C@@H]2OP(=O)(O)OC[C@H]2O[C@H]1n1cnc2c(N)ncnc21.CN(C)c1ccncc1