ent-Lamivudine Triphosphate Triethylammonium Salt

CAS: 2699949-69-2

Ref. TR-L173245

Informação sobre produto

• Nome: ent-Lamivudine Triphosphate Triethylammonium Salt
• Sinónimos: ((2R,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolan-2-yl)methyl Tetrahydrogen Triphosphate Triethylammonium Salt

Descrição

Applications ent-Lamivudine Triphosphate Triethylammonium Salt is a metabolite of Lamivudine (L172500), which is a potent nucleoside reverse transcriptase inhibitor. Antiviral. Lamivudine has been used for treatment of chronic hepatitis B.
References Burgess, K., et al.: Chem. Rev., 100, 2047 (2000), Gallois-Montbrun, S., et al.: Biochem. Pharmacol., 68, 1749 (2004); Morris, D.M., J. Pharm. Biomed. Anal., 12, 255 (1944), Nevens, B.F., et al.: Gastroenterology, 113, 1258 (1997), Perry, C.M., et al.: Drugs, 53, 657 (1977)

• Marca: TRC

Propriedades químicas

• Peso molecular: 570.07155
• Fórmula: C₈H₁₄N₃O₁₂P₃SC₆H₁₅N
• Cor/forma: Neat
• InChI: InChI=1S/C8H14N3O12P3S.C6H15N/c9-5-1-2-11(8(12)10-5)6-4-27-7(21-6)3-20-25(16,17)23-26(18,19)22-24(13,14)15;1-4-7(5-2)6-3/h1-2,6-7H,3-4H2,(H,16,17)(H,18,19)(H2,9,10,12)(H2,13,14,15);4-6H2,1-3H3/t6-,7+;/m1./s1
• Chave InChI: InChIKey=MXNICHMIOGGOHH-HHQFNNIRSA-N
• SMILES: CCN(CC)CC.Nc1ccn([C@H]2CS[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c(=O)n1