Leurosine Sulfate

CAS: 54081-68-4

Ref. TR-L330800

Informação sobre produto

• Nome: Leurosine Sulfate
• Sinónimos: 4β-Acetoxy-3’α,4’-epoxy-3-hydroxy-16-methoxy-(4’α H)-vincaleukoblast-6-ene-23,22’-dioic Acid Dimethyl Ester Sulfate, Vinleurosine Sulfate, Lilly 32645, Vinorelbine Impurity E (EP) Sulfate, 4-Acetoxy-3’a,4’-epoxy-3-hydroxy-16-methoxy-(4’a H)-vincaleukoblast-6-ene-23,22’-dioic Acid Dimethyl Ester Sulfate

Descrição

Applications A new antitumor derivative of Vinblastine; a dimeric Vinca alkaloid for cancer therapy.
References Chakravarty, et al.: J. Med. Chem., 26(5), 638 (1983), Christensson., et al.: Eu.r J. Biochem., 194, 755 (1990), Mayer, et al.: J. Med. Chem., 34, 3029 (1991), Yu, H., et al.: Clin. Biochem., 27, 75 (1994)

• Marca: TRC

Propriedades químicas

• Peso molecular: 1716.00
• Fórmula: C₄₆H₅₆N₄O₉·H₂O₄S
• Cor/forma: Neat
• InChI: InChI=1S/2C46H56N4O9.H2O4S/c2*1-8-42-16-12-18-50-20-17-44(37(42)50)30-21-31(34(55-5)22-33(30)48(4)38(44)46(54,41(53)57-7)39(42)58-26(3)51)45(40(52)56-6)23-27-24-49(25-43(9-2)36(27)59-43)19-15-29-28-13-10-11-14-32(28)47-35(29)45;1-5(2,3)4/h2*10-14,16,21-22,27,36-39,47,54H,8-9,15,17-20,23-25H2,1-7H3;(H2,1,2,3,4)/t2*27-,36-,37-,38+,39+,42+,43+,44+,45-,46-;/m00./s1
• SMILES: CC[C@@]12C=CCN3CC[C@]4(c5cc([C@]6(C(=O)OC)C[C@H]7C[N@@](CCc8c6[nH]c6ccccc86)C[C@@]6(CC)O[C@H]76)c(OC)cc5N(C)[C@H]4C(O)(C(=O)OC)[C@@H]1OC(C)=O)[C@@H]32