Linezolid N-Oxide

CAS: 189038-36-6

Ref. TR-L466530

Informação sobre produto

• Nome: Linezolid N-Oxide
• Sinónimos: N-[[(5S)-3-[3-fluoro-4-(4-oxido-4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-acetamide, Acetamide, N-[[3-[3-fluoro-4-(4-oxido-4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-, (S)- (9CI)

Descrição

Applications Linezolid N-oxide is a derivative of Linezolid (L466500), an oxazolidinone antimicrobial that is used to treat infections against gram-positive bacteria, especially those that are drug-resistant (such as Vancomycin [HCl: V096500] resistant enterococci). Linezolid works by inhibiting bacterial protein synthesis.
References Dennis, L., et al.: Clin. Infect. Dis., 34, 1481 (2002); Clemett, D. & Markham, A.: Drugs, 59, 815 (2000); Gonzales, R., et al.: Lancet, 357, 1179 (2001); Tsiodras, S., et al.: Lancet, 358, 207 (2001)

• Marca: TRC

Propriedades químicas

• Peso molecular: 353.35
• Fórmula: C₁₆H₂₀FN₃O₅
• Cor/forma: White To Off-White
• InChI: InChI=1S/C16H20FN3O5/c1-11(21)18-9-13-10-19(16(22)25-13)12-2-3-15(14(17)8-12)20(23)4-6-24-7-5-20/h2-3,8,13H,4-7,9-10H2,1H3,(H,18,21)/t13-/m0/s1
• Chave InChI: InChIKey=CMFKNYFIQWSUNN-ZDUSSCGKSA-N
• SMILES: CC(=O)NC[C@H]1CN(c2ccc([N+]3([O-])CCOCC3)c(F)c2)C(=O)O1