Lopinavir D-Valine Diastereomer-d9

CAS: 1623021-24-8

Ref. TR-L469547

Informação sobre produto

• Nome: Lopinavir D-Valine Diastereomer-d9
• Sinónimos: (R)-N-((2S,4S,5S)-5-(2-(2,6-Dimethylphenoxy)acetamido)-4-hydroxy-1,6-diphenylhexan-2-yl)-3-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanamide-d9
• CAS: 1623021-24-8

Descrição

Applications Lopinavir D-Valine Diastereomer-d9 is the isotope labelled analog of Lopinavir D-Valine Diastereomer. Lopinavir D-Valine Diastereomer is a metabolite of Lopinavir (L469480); a selective HIV protease inhibitor and antiviral. It is a COVID19-related research product.
References Sham, H.L., et al.: Antimicrob. Ag. Chemother., 42, 3218 (1998); Kumar, G.N., et al.: Drug Metab. Dispos., 27, 86 (1999); Murphy, R.L., et al.: Antiviral Ther., 4, Suppl. 3, 85 (1999)

• Marca: TRC

Propriedades químicas

• Peso molecular: 637.86
• Fórmula: C₃₇H₃₉D₉N₄O₅
• Cor/forma: Neat
• InChI: InChI=1S/C37H48N4O5/c1-25(2)34(41-20-12-19-38-37(41)45)36(44)39-30(21-28-15-7-5-8-16-28)23-32(42)31(22-29-17-9-6-10-18-29)40-33(43)24-46-35-26(3)13-11-14-27(35)4/h5-11,13-18,25,30-32,34,42H,12,19-24H2,1-4H3,(H,38,45)(H,39,44)(H,40,43)/t30-,31-,32-,34+/m0/s1/i3D3,4D3,11D,13D,14D
• Chave InChI: InChIKey=KJHKTHWMRKYKJE-PSFCBMKISA-N
• SMILES: [2H]c1c([2H])c(C([2H])([2H])[2H])c(OCC(=O)N[C@@H](Cc2ccccc2)[C@@H](O)C[C@H](Cc2ccccc2)NC(=O)[C@H](C(C)C)N2CCCNC2=O)c(C([2H])([2H])[2H])c1[2H]