Loxoprofen

CAS: 68767-14-6

Ref. TR-L472905

Informação sobre produto

• Nome: Loxoprofen
• Sinónimos: 2-[4-[(2-oxocyclopentyl)methyl]phenyl]propanoic acid, 2-[4-(2-Oxo-Cyclopentylmethyl)-Phenyl]-Propionic Acid, 2-[4-[(2-Oxocyclopentan-1-Yl)Methyl]Phenyl]Propionic Acid, 2-[4-[(2-Oxocyclopentyl)methyl]phenyl]propionic acid, 2-{4-[(2-Oxocyclopentyl)Methyl]Phenyl}Propanoic Acid, A-Methyl-4-[(2-Oxocyclopentyl)Methyl]Benzeneacetic Acid, Alpha-Methyl-4-[(2-Oxocyclopentyl)Methyl]Benzeneacetic Acid, Benzeneacetic acid, α-methyl-4-[(2-oxocyclopentyl)methyl]-, Ioxoprofen, Koloxo, Loxoprofen Acid

Descrição

Applications Loxoprofen is a non-selective nonsteroidal anti-inflammatory drug (NSAID) that has been effective in reducing atherosclerosis in mice by reducing inflammation. Loxoprofen becomes active after metabolism in the body and inhibits the activation of cyclooxygenase.
References Masahide H. et al.: J Clin Biochem Nutr., 47, 138 (2010); Noguchi, M. et al.: Biolog. Pharmac. Bull., 28, 2075 (2005); Hyun, J. et al.: Arch. Pharm. Res., 24, 541 (2001);

• Marca: TRC

Propriedades químicas

• Peso molecular: 246.30
• Fórmula: C₁₅H₁₈O₃
• Cor/forma: White To Off-White
• InChI: InChI=1S/C15H18O3/c1-10(15(17)18)12-7-5-11(6-8-12)9-13-3-2-4-14(13)16/h5-8,10,13H,2-4,9H2,1H3,(H,17,18)
• Chave InChI: InChIKey=YMBXTVYHTMGZDW-UHFFFAOYSA-N
• SMILES: CC(C(=O)O)c1ccc(CC2CCCC2=O)cc1