Lubiprostone-d7

CAS: 1217675-13-2

Ref. TR-L473503

Informação sobre produto

• Nome: Lubiprostone-d7
• Sinónimos: (11a)-16,16-Difluoro-11-hydroxy-9,15-dioxo-prostan-1-oic Acid-d7, Ru 0211-d7

Descrição

Applications Labelled Lubiprostone is a bicyclic fatty acid metabolite analog of Prostaglandin E1. It activates specific chloride channels in the gastrointestinal tract to stimulate intestinal fluid secretion, increase gastrointestinal transit, and improve symptoms of constipation.
References Farthing, M., et al.: Drugs, 56, 11 (1998), Pare, P., et al.: Am. J. Gastroenterol., 96, 3130 (2001), Sloots, C., et al.: Aliment. Pharmacol. Ther., 16, 759 (2002), Coremans, G., et al.: Digestion, 67, 82 (2003),

• Marca: TRC

Propriedades químicas

• Peso molecular: 397.51
• Fórmula: C₂₀H₂₅D₇F₂O₅
• Cor/forma: Neat
• InChI: InChI=1S/C20H32F2O5/c1-2-3-12-20(21,22)18(25)11-10-15-14(16(23)13-17(15)24)8-6-4-5-7-9-19(26)27/h14-15,17,24H,2-13H2,1H3,(H,26,27)/t14-,15-,17-/m1/s1/i1D3,2D2,3D2
• Chave InChI: InChIKey=DBVFKLAGQHYVGQ-QHZIEZROSA-N
• SMILES: [2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])CC(F)(F)C(=O)CC[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)O