(5S)-N-(Methoxycarbonyl)-L-valyl-5-methyl-L-proline

CAS: 1335316-40-9

Ref. TR-M261343

Informação sobre produto

• Nome: (5S)-N-(Methoxycarbonyl)-L-valyl-5-methyl-L-proline
• Sinónimos: N-[2-(S)-[(Methoxycarbonyl)amino]-3-methylbutyryl]-(5S)-5-methyl-L-proline, (2S,4S)-1-(tert-butoxycarbonyl)-4-(methoxyMethyl)pyrrolidine-2-carboxylic acid, (2S,5S)-1-((S)-2-((methoxycarbonyl)amino)-3-methylbutanoyl)-5-methylpyrrolidine-2-carboxylic acid, (2S,5S)-1-((methoxycarbonyl)-L-valyl)-5-methylpyrrolidine-2-carboxylic acid, <span class="text-smallcaps">L</smallcap>-Proline, N-(methoxycarbonyl)-<smallcap>L</span>-valyl-5-methyl-, (5S)-, N-[2-(S)-[(Methoxycarbonyl)amino]-3-methylbutyryl]-(5S)-5-Methyl-<span class="text-smallcaps">L</span>-proline

Descrição

Applications (5S)-N-(Methoxycarbonyl)-L-valyl-5-methyl-L-proline is an antiviral agent and Velpatasvir (V116000) intermediate. Velpatasvir is a NS5A inhibitor in patients with hepatitis C (HCV) infection.
References Feld, J. J., et al.: N. Engl. J. Med. 373, 2599 (2015); Gane, E. J., et al.: Gastroenterol., 151, 448 (2016);

• Marca: TRC

Propriedades químicas

• Peso molecular: 286.32
• Fórmula: C₁₃H₂₂N₂O₅
• Cor/forma: Off-White to Pale Beige Solid
• InChI: InChI=1S/C13H22N2O5/c1-7(2)10(14-13(19)20-4)11(16)15-8(3)5-6-9(15)12(17)18/h7-10H,5-6H2,1-4H3,(H,14,19)(H,17,18)/t8-,9-,10-/m0/s1
• Chave InChI: InChIKey=PNAXKGVRCAXIJK-GUBZILKMSA-N
• SMILES: COC(=O)N[C@H](C(=O)N1[C@@H](C)CC[C@H]1C(=O)O)C(C)C