3-Methoxy-10H-phenothiazine

CAS: 1771-19-3

Ref. TR-M265405

Informação sobre produto

• Nome: 3-Methoxy-10H-phenothiazine
• Sinónimos: 3-Methoxyphenothiazine, 10H-Phenothiazine, 3-methoxy-, Phenothiazine, 3-methoxy-

Descrição

Applications 3-Methoxy-10H-phenothiazine is used in the synthesis of 10-Dechlorovancomycin (D226740), which is an impurity of Vancomycin (V096500, HCl salt) which is an amphoteric glycopeptide antibiotic produced by Streptomyces orientalis discovered in soil. Vancomycin inhibits bacterial cell wall synthesis by binding to peptidoglycan.
References Marshall, F.J., et al.: J. Med. Chem., 8, 18 (1965), Cunha, B.A., et al.: Med. Clin. North Am., 79, 817 (1995), Li, L., et al.: Ther. Drug Monit., 17, 366 (1995)

• Marca: TRC

Propriedades químicas

• Peso molecular: 229.3
• Fórmula: C₁₃H₁₁NOS
• Cor/forma: Neat
• InChI: InChI=1S/C13H11NOS/c1-15-9-6-7-11-13(8-9)16-12-5-3-2-4-10(12)14-11/h2-8,14H,1H3
• Chave InChI: InChIKey=NKRGJNZQQYCJHD-UHFFFAOYSA-N
• SMILES: COc1ccc2c(c1)Sc1ccccc1N2