N-[2-(o-Methoxyphenoxy)ethyl]phthalimide

CAS: 26646-63-9

Ref. TR-M265630

Informação sobre produto

• Nome: N-[2-(o-Methoxyphenoxy)ethyl]phthalimide
• Sinónimos: 2-[2-(2-Methoxyphenoxy)ethyl]-1H-isoindole-1,3(2H)-dione

Descrição

Applications N-[2-(o-Methoxyphenoxy)ethyl]phthalimide is a useful synthetic intermediate in the synthesis of Carvedilol (C184625); a nonselective β-adrenergic blocker with α1-blocking activity. Carvedilol is an antihypertensive used in the treatment of congestive heart failure.
References Hirohashi, M., et al.: Arzneim.-Forsch., 40, 735 (1990); Packer, M., et al.: N. Engl. J. Med., 334, 1349 (1996); Kumar, B.A., et al.: Org. Chem., 6, 70 (2010)

• Marca: TRC

Propriedades químicas

• Peso molecular: 297.31
• Fórmula: C₁₇H₁₅NO₄
• Cor/forma: White to Off-White Solid
• InChI: InChI=1S/C17H15NO4/c1-21-14-8-4-5-9-15(14)22-11-10-18-16(19)12-6-2-3-7-13(12)17(18)20/h2-9H,10-11H2,1H3
• Chave InChI: InChIKey=WRBSZMMWHCAUKD-UHFFFAOYSA-N
• SMILES: COc1ccccc1OCCN1C(=O)c2ccccc2C1=O