Methyl 3-Amino-4-methylbenzoate-D6

CAS: 18595-18-1

Ref. TR-M286816

Informação sobre produto

• Nome: Methyl 3-Amino-4-methylbenzoate-D6
• Sinónimos: methyl 3-amino-2,5,6-trideuterio-4-(trideuteriomethyl)benzoate, 2-Methyl-5-methoxycarbonylaniline, 3-Amino-4-Methylbenzoic Acid Methyl Ester, 3-Amino-p-toluic acid methyl ester, Benzoic acid, 3-amino-4-methyl-, methyl ester, Methyl 3-amino-4-methyl benzoate, Methyl 3-amino-4-methylbenzoic acid, Methyl-3-amino-4-methylbenozate, Methyl4-Methyl-3-Aminobenzoate, NSC 356832, p-Toluic acid, 3-amino-, methyl ester
• CAS: 18595-18-1

Descrição

Applications Methyl 3-Amino-4-methylbenzoate-D6 is an intermediate in the synthesis of Nilotinib-d6 (N465303), which is the labeled analogue of Nilotinib (N465300), which might be useful in treatment of chronic myelogenous leukemia.
References Corbin, A., et al.: J. Biol. Chem., 277, 32214(2002), Golemovic, M., et al.: Clin. Cancer Res., 11, 4941 (2005), Gleixner, K., et al.: Blood, 107, 752 (2006), Nicolini, F., et al.: Leukemia, 20, 1061 (2006),

• Marca: TRC

Propriedades químicas

• Peso molecular: 171.226
• Fórmula: C₉H₅D₆NO₂
• Cor/forma: Neat
• InChI: InChI=1S/C9H11NO2/c1-6-3-4-7(5-8(6)10)9(11)12-2/h3-5H,10H2,1-2H3/i1D3,3D,4D,5D
• Chave InChI: InChIKey=YEPWCJHMSVABPQ-YFNZQJCKSA-N
• SMILES: [2H]c1c([2H])c(C([2H])([2H])[2H])c(N)c([2H])c1C(=O)OC