N-Methyl-N-(3-chloropropyl)homoveratrylamine Hydrochloride

CAS: 36770-75-9

Ref. TR-M295155

Informação sobre produto

• Nome: N-Methyl-N-(3-chloropropyl)homoveratrylamine Hydrochloride
• Sinónimos: N-(3-Chloropropyl)-3,4-dimethoxy-N-methylbenzeneethanamine Hydrochloride, SR 45813 Hydrochloride, Verapamil EP Impurity D (HCl), 3-chloro-N-[2-(3,4-dimethoxyphenyl)ethyl]-N-methylpropan-1-amine hydrochloride, Benzeneethanamine, N-(3-chloropropyl)-3,4-dimethoxy-N-methyl-, hydrochloride, Benzeneethanamine, N-(3-chloropropyl)-3,4-dimethoxy-N-methyl-, hydrochloride (1:1), N-(3-Chloropropyl)-3,4-dimethoxy-N-methylphenethylamine hydrochloride

Descrição

Impurity Verapamil EP Impurity D
Applications N-Methyl-N-(3-chloropropyl)homoveratrylamine, is a novel class of calcium channel blocker, which has shown to have the ability to enhance ricin A-chain immunotoxins (RTA-IT) activity in vitro and in vivo. Also is an impurity of Verapamil (V125000), a calcium channel blocker, adrenergic antagonist (1). Antihypertensive; antianginal; antiarrhythmic (2) (class IV).
References 1. Atlas, D. et al.: Proc Natl Acad Sci U S A. 1981 Feb;78(2):1237-41.2. Yang, W. et al.: Cell Physiol Biochem. 2017 Apr 17;41(5):2104-2116

• Marca: TRC

Propriedades químicas

• Peso molecular: 271.78 + (36.46)
• Fórmula: C₁₄H₂₂ClNO₂·HCl
• Cor/forma: Neat
• InChI: InChI=1S/C14H22ClNO2.ClH/c1-16(9-4-8-15)10-7-12-5-6-13(17-2)14(11-12)18-3;/h5-6,11H,4,7-10H2,1-3H3;1H
• Chave InChI: InChIKey=OXJTYZRBMQFHMP-UHFFFAOYSA-N
• SMILES: COc1ccc(CCN(C)CCCCl)cc1OC.Cl