Methyl 5-Methoxy-2-methylindole-3-acetate-d3

CAS: 7588-36-5

Ref. TR-M320482

Informação sobre produto

• Nome: Methyl 5-Methoxy-2-methylindole-3-acetate-d3
• Sinónimos: 5-Methoxy-2-methyl-1H-indole-3-acetic-d3 Acid Methyl Ester, 5-Methoxy-2-methylindole-3-acetic-d3 Acid Methyl Ester
• Marca: TRC
• Descrição: Applications Methyl 5-Methoxy-2-methylindole-3-acetate-d3 is labelled Methyl 5-Methoxy-2-methylindole-3-acetate (M320480), which is an intermediate in the preparation of Indomethacin. Methyl 5-Methoxy-2-methylindole-3-acetate-d3, itself is an intermediate in the synthesis of N-Deschlorobenzoyl Indomethacin-d3 (D288847), the labeled analogue of N-Deschlorobenzoyl Indomethacin (D288845), a metabolite of Indomethacin (I641000).References O'Brien, W., et al.: Clin. Pharmacol. Ther., 9, 94 (1968), Duggan, D., et al.: J. Pharmacol. Exp. Ther., 181, 563 (1972), Abourashed, E., et al.: Curr. Med. Chem., 6, 359 (1999), Chatterjee, P., et al.: J. Nat. Prod., 62, 761 (1999), Kalgutkar, A.S., et al.: Bioorg. Med. Chem., 13, 6810 (2005)

Propriedades químicas

• Peso molecular: 236.282
• Fórmula: C₁₃D₃H₁₂NO₃
• Cor/forma: Neat
• InChI: InChI=1S/C13H15NO3/c1-8-10(7-13(15)17-3)11-6-9(16-2)4-5-12(11)14-8/h4-6,14H,7H2,1-3H3/i2D3
• Chave InChI: InChIKey=JYUNCKSXPPDNRM-BMSJAHLVSA-N
• SMILES: [2H]C([2H])([2H])Oc1ccc2[nH]c(C)c(CC(=O)OC)c2c1