4-Methylthiazole-5-carboxylic Acid

CAS: 20485-41-0

Ref. TR-M330310

Informação sobre produto

• Nome: 4-Methylthiazole-5-carboxylic Acid
• Sinónimos: 4-Methyl-1,3-thiazole-5-carboxylic Acid, 4-Methyl-5-thiazolecarboxylic Acid, 4-Methyl-1,3-Thiazole-5-Carboxylic Acid, 4-Methyl-5-thiazolecarboxylic acid, 4-Methyl-thiazole-5-carboxylic acid, 4-Methylthiazole-5-Carboxylate, 5-Thiazolecarboxylic acid, 4-methyl-
• CAS: 20485-41-0

Descrição

Applications 4-Methylthiazole-5-carboxylic acid is used as a reagent to synthesize thiazolylimidazolidinone compounds that act as Stearoyl-CoA desaturase-1 (SCD1) inhibitors. These SCD1 inhibitors are used in the treatment of metabolic diseases. 4-Methylthiazole-5-carboxylic acid is also used as a reagent to synthesize 4-Methyl-5-formylthiazole, an important intermediate in the synthesis of Cefditoren pivoxil (C242700).
References Bai, N., et al.: Molecules, 13, 943 (2008); Sun, S., et al.: Bioorg. Med. Chem. Lett., 24, 520 (2014)

• Marca: TRC

Propriedades químicas

• Peso molecular: 143.16
• Fórmula: C₅H₅NO₂S
• Cor/forma: Off-White Solid
• InChI: InChI=1S/C5H5NO2S/c1-3-4(5(7)8)9-2-6-3/h2H,1H3,(H,7,8)
• Chave InChI: InChIKey=ZGWGSEUMABQEMD-UHFFFAOYSA-N
• SMILES: Cc1ncsc1C(=O)O