MG 132

CAS: 133407-82-6

Ref. TR-M340900

Informação sobre produto

• Nome: MG 132
• Sinónimos: (S)-N-[(Phenylmethoxy)carbonyl]-L-leucyl-N-(1-formyl-3-methylbutyl)-L-leucinamide, Calpain inhibitor IV-2, <span class="text-smallcaps">L</smallcap>-Leucinamide, N-[(phenylmethoxy)carbonyl]-<smallcap>L</span>-leucyl-N-(1-formyl-3-methylbutyl)-, (S)-, <span class="text-smallcaps">L</smallcap>-Leucinamide, N-[(phenylmethoxy)carbonyl]-<smallcap>L</span>-leucyl-N-[(1S)-1-formyl-3-methylbutyl]-, Calpain Inhibitor IV, Mg-132, N-[(Phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</smallcap>-leucyl-N-[(1S)-1-formyl-3-methylbutyl]-<smallcap>L</span>-leucinamide, N-[(benzyloxy)carbonyl]-L-leucyl-N-[(2S)-4-methyl-1-oxopentan-2-yl]-L-leucinamide, N-[(benzyloxy)carbonyl]leucyl-N-[(2S)-4-methyl-1-oxopentan-2-yl]leucinamide, Z-Leu-Leu-Leu-aldehyde, N-[(Phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-formyl-3-methylbutyl]-L-leucinamide, L-Leucinamide, N-[(phenylmethoxy)carbonyl]-L-leucyl-N-(1-formyl-3-methylbutyl)-, (S)-, L-Leucinamide, N-[(phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-formyl-3-methylbutyl]-

Descrição

Stability Hygroscopic
Applications MG 132 is a potent, membrane-permeable proteasome inhibitor. It induces neurite outgrowth in PC12 cells. Neuroprotective product.
References Lee, D., et al.: Trends in Cell Biol., 8, 397 (1998); Tsubuki, S., et al.: J. Biochem., 119., 572 (1996); Grimm, L., et al.: EMBO J., 15, 3835 (1996)

• Marca: TRC

Propriedades químicas

• Peso molecular: 475.62
• Fórmula: C₂₆H₄₁N₃O₅
• Cor/forma: Neat
• InChI: InChI=1S/C32H47F5O3S/c1-30-17-15-26-25-12-11-24(38)21-23(25)20-22(29(26)27(30)13-14-28(30)39)10-7-5-3-2-4-6-8-18-41(40)19-9-16-31(33,34)32(35,36)37/h11-12,21-22,26-29,38-39H,2-10,13-20H2,1H3/t22-,26-,27+,28-,29+,30-,41?/m0/s1
• Chave InChI: InChIKey=VWUXBMIQPBEWFH-STSJHAPQSA-N
• SMILES: C[C@]12CC[C@H]3c4ccc(O)cc4C[C@H](CCCCCCCCCS(=O)CCCC(F)(F)C(F)(F)F)[C@H]3[C@H]1CC[C@@H]2O