Mocetinostat

CAS: 726169-73-9

Ref. TR-M481090

Informação sobre produto

• Nome: Mocetinostat
• Sinónimos: N-(2-aminophenyl)-4-[[(4-pyridin-3-ylpyrimidin-2-yl)amino]methyl]benzamide, Mg 0103, Mgcd 0103, N-(2-Aminophenyl)-4-[[[4-(3-pyridinyl)-2-pyrimidinyl]amino]methyl]benzamide, N-(2-aminophenyl)-4-((4-pyridin-3-ylpyrimidin-2-ylamino)methyl)benzamide, N-(2-aminophenyl)-4-({[4-(pyridin-3-yl)pyrimidin-2-yl]amino}methyl)benzamide, benzamide, N-(2-aminophenyl)-4-[[[4-(3-pyridinyl)-2-pyrimidinyl]amino]methyl]-

Descrição

Applications Mocetinostat is a multi-targeted histone deacetylase inhibitor used in cancer therapy. Mocetinostat is undergoing clinical trials for the treatment of various cancers including follicular lymphoma, Hodgkin’s lymphoma and acute myelogenous leukemia.
References Ai, T., et al.: Curr. Med. Chem., 19, 475 (2012); Cacasin, M.A., et al.: Circulation Rsch., 110, 739 (2012); Younes, A., et al.: Lancet Oncol., 12, 1222 (2011);

• Marca: TRC

Propriedades químicas

• Peso molecular: 396.44
• Fórmula: C₂₃H₂₀N₆O
• Cor/forma: Neat
• InChI: InChI=1S/C23H20N6O/c24-19-5-1-2-6-21(19)28-22(30)17-9-7-16(8-10-17)14-27-23-26-13-11-20(29-23)18-4-3-12-25-15-18/h1-13,15H,14,24H2,(H,28,30)(H,26,27,29)
• Chave InChI: InChIKey=HRNLUBSXIHFDHP-UHFFFAOYSA-N
• SMILES: Nc1ccccc1NC(=O)c1ccc(CNc2nccc(-c3cccnc3)n2)cc1