Dimethylaminocarboxymethyl POC Tenofovir (Mixture of Diastereomers)

CAS: 147127-20-6

Ref. TR-M540865

Informação sobre produto

• Nome: Dimethylaminocarboxymethyl POC Tenofovir (Mixture of Diastereomers)
• Sinónimos: (((((Isopropoxycarbonyl)oxy)methoxy)phosphoryl)oxy)methyl-dimethylcarbamate Tenofovir, P-[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]phosphonic acid, Phosphonic acid, [[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, (R)-9-(2-Phosphonomethoxypropyl)adenine, Phosphonic acid, P-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, Phosphonic acid, [[2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, (R)-

Descrição

Impurity Tenofovir Impurity
Stability Light Sensitive
Applications An impurity of Tenofovir (T018500). Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor. It is used as an anti-HIV agent.
References Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007);

• Marca: TRC

Propriedades químicas

• Peso molecular: 504.431
• Fórmula: C₁₈H₂₉N₆O₉P
• Cor/forma: Neat
• InChI: InChI=1S/C18H29N6O9P/c1-12(2)33-18(26)29-10-32-34(27,31-9-28-17(25)23(4)5)11-30-13(3)6-24-8-22-14-15(19)20-7-21-16(14)24/h7-8,12-13H,6,9-11H2,1-5H3,(H2,19,20,21)/t13-,34?/m1/s1
• Chave InChI: InChIKey=JRHZRYZACVNIRJ-BCTWOLBCSA-N
• SMILES: CC(C)OC(=O)OCOP(=O)(CO[C@H](C)Cn1cnc2c(N)ncnc21)OCOC(=O)N(C)C