Nalmefene-d3

CAS: 55096-26-9

Ref. TR-N284402

Informação sobre produto

• Nome: Nalmefene-d3
• Sinónimos: (5a)-17-(Cyclopropylmethyl-d3)-4,5-epoxy-6-methylenemorphinan-3,14-diol, 6-Deoxo-6-methylenenaltrexone-d3, 6-Desoxy-6-methylenenaltrexone-d3, JF 1-d3, Nalmetrene-d3, ORF 11676-d3, (5Alpha)-17-(Cyclopropylmethyl)-6-Methylidene-4,5-Epoxymorphinan-3,14-Diol, (5alpha)-17-(Cyclopropylmethyl)-4,5-epoxy-6-methylenemorphinon-3,14-diol, (5α)-17-(Cyclopropylmethyl)-4,5-epoxy-6-methylenemorphinan-3,14-diol, 17-(Cyclopropylmethyl)-4,5alpha-epoxy-6-methylenemorphinan-3,14-diol, 6-Deoxo-6-methylenenaltrexone, 6-Desoxy-6-methylenenaltrexone, 9a-(Cyclopropylmethyl)-4,5alpha-epoxy-6-methylen-3,14-morphinandiol, Alcofene, Arthene, Cervene, Cessal, Fenarc, Hsdb 6761, Incystene, Jf 1, Jkb 121, Morphinan-3,14-diol, 17-(cyclopropylmethyl)-4,5-epoxy-6-methylene-, (5alpha)-, Morphinan-3,14-diol, 17-(cyclopropylmethyl)-4,5-epoxy-6-methylene-, (5α)-, Nalmefene [USAN:INN:BAN], Nalmefeno, Nalmefeno [INN-Spanish], Nalmefenum, Nalmefenum [INN-Latin], Nalmetrene, Nalmetreno, Nalmetreno [INN-Spanish], Nalmetrenum, Nalmetrenum [INN-Latin], Nocarex, Orf 11676, Soberal, Srd 174, Unii-Tov02Tdp9I
• CAS: 55096-26-9

Descrição

Applications A structural labelled analog of Naltrexone (N285780) with opiate antagonist activity used in pharmaceutical treatment of alcoholism. Other pharmacological applications of this compound aim to reduce food cravings, drug abuse and pulmonary disease in affected individuals. Used as an opioid-induced tranquilizer on large animals in the veterinary industry. Narcotic antagonist.
References Brittain, H.G., et al.: Anal. Profiles Drug Subs. Excip., 24, 351 (1996), Anton, R., et al.: J. Clin. Psychopharmacol., 24, 421 (2004), Bart, G., et al.: Neuropsychopharmacol., 30, 2254 (2005), Wu, X., et al.: Chem. Pharmacol. Bull., 54, 977 (2006),

• Marca: TRC

Propriedades químicas

• Peso molecular: 342.45
• Fórmula: C₂₁H₂₂D₃NO₃
• Cor/forma: Neat
• InChI: InChI=1S/C21H25NO3/c1-12-6-7-21(24)16-10-14-4-5-15(23)18-17(14)20(21,19(12)25-18)8-9-22(16)11-13-2-3-13/h4-5,13,16,19,23-24H,1-3,6-11H2/t16-,19+,20+,21-/m1/s1/i11D2,13D
• Chave InChI: InChIKey=WJBLNOPPDWQMCH-TVFUAGGXSA-N
• SMILES: [2H]C1(C([2H])([2H])N2CC[C@]34c5c6ccc(O)c5O[C@H]3C(=C)CC[C@@]4(O)[C@H]2C6)CC1