β-Nicotinamide Adenine Dinucleotide Sodium Salt Hydrate

CAS: 20111-18-6 53-84-9

Ref. TR-N407775

Informação sobre produto

• Nome: β-Nicotinamide Adenine Dinucleotide Sodium Salt Hydrate
• Sinónimos: Codehydrase I sodium salt hydrate, Coenzyme I sodium salt hydrate

Descrição

Stability Light Sensitive
Applications β-Nicotinamide Adenine Dinucleotide is a coeznyme consisting of an adenine base and a nicotinamide base connected by a pair of bridging phosphate group. β-Nicotinamide Adenine Dinucleotide acts as a coenzyme in redox reactions, as a donor of ADP-ribose moieties in ADP-ribosylation reactions and also as a precursor of the second messenger molecule cyclic ADP-ribose. β-Nicotinamide Adenine Dinucleotide also acts as a substrate for bacterial DNA ligases and a group of enzymes called sirtuins that use NAD+ to remove acetyl groups from proteins.
References Dudev, T. et al.: J. Am. Chem. Soc., 132, 16533 (2010); Kerbey, A. et al.: Biochem. J., 154, 327 (1976); Lahiri, S.D. et al.: ACS Chem. Biol., 7, 571 (2012);

• Marca: TRC

Propriedades químicas

• Peso molecular: 685.41
• Fórmula: C₂₁H₂₆N₇O₁₄P₂·Na·xH₂O
• Pureza: >85%
• Cor/forma: Neat
• InChI: InChI=1S/C21H27N7O14P2.Na/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33;/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37);/q;+1/p-1/t10-,11-,13-,14-,15-,16-,20-,21-;/m1./s1
• SMILES: NC(=O)c1ccc[n+]([C@H]2O[C@@H](COP(=O)([O-])OP(=O)(O[Na])OC[C@H]3O[C@@H](n4cnc5c(N)ncnc54)[C@H](O)[C@@H]3O)[C@@H](O)[C@H]2O)c1