Nilotinib Regio Isomer

CAS: 641571-15-5

Ref. TR-N465320

Informação sobre produto

• Nome: Nilotinib Regio Isomer
• Sinónimos: 4-methyl-N-[3-(5-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-, 4-Methyl-N-[3-(5-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzamide, 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-N-[5-(5-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl]benzamide, 4-Methyl-N-[3-(5-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(pyridin-3-yl)pyrimidin-2-yl]amino]benzamide, Nilotinib isomer
• CAS: 641571-15-5

Descrição

Applications Nilotinib Regio Isomer is a more potent Bcr-Abl tyrosine kinase inhibitor for the treatment of patients with myelogenous leukemia. It is a COVID19-related research product.
References Wei-Sheng H., et al.: Synthesis, 14, 2121 (2007); Bilbe, G.,et al.: From PCT Int. Appl. (2005), WO 2005039586 A1 20050506

• Marca: TRC

Propriedades químicas

• Peso molecular: 529.52
• Fórmula: C₂₈H₂₂F₃N₇O
• Cor/forma: Neat
• InChI: InChI=1S/C28H22F3N7O/c1-17-5-6-19(10-25(17)37-27-34-9-7-24(36-27)20-4-3-8-32-15-20)26(39)35-22-11-21(28(29,30)31)12-23(13-22)38-16-33-14-18(38)2/h3-16H,1-2H3,(H,35,39)(H,34,36,37)
• Chave InChI: InChIKey=LVVDYLLEWIHKDY-UHFFFAOYSA-N
• SMILES: Cc1ccc(C(=O)Nc2cc(-n3cncc3C)cc(C(F)(F)F)c2)cc1Nc1nccc(-c2cccnc2)n1