rac-N’-Nitroso Nornicotine

CAS: 80508-23-2

Ref. TR-N535000

Informação sobre produto

• Nome: rac-N’-Nitroso Nornicotine
• Sinónimos: N-Nitrosonornicotine, 1-Nitroso-2-(3-pyridyl)pyrrolidine, 3-(1-Nitroso-2-pyrrolidinyl)pyridine, Pyridine, 3-(1-nitroso-2-pyrrolidinyl)-

Descrição

Applications N'-Nitrosonornicotine (NNN) is a tobacco alkaloid known as esophageal carcinogen. NNN is the cause of esophageal and oral cavity cancer in smokers and snuff dippers. The studies showed that the carcinogenicity of (S)-NNN, the predominant enantiomer in tobacco products, may be greater than that of (R)-NNN or racemic NNN.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Anto, R., et al.: Carcinogenesis, 23, 1511 (2002), Pfeifer, G., et al.: Oncogene, 21, 7435 (2002), Shishodia, S., et al.: Cancer Res., 64, 5004 (2004), Jin, Z., et al.: J. Biol. Chem., 279, 23837 (2004),

• Marca: TRC

Propriedades químicas

• Peso molecular: 177.20
• Fórmula: C₉H₁₁N₃O
• Cor/forma: Light Yellow
• InChI: InChI=1S/C9H11N3O/c13-11-12-6-2-4-9(12)8-3-1-5-10-7-8/h1,3,5,7,9H,2,4,6H2
• Chave InChI: InChIKey=XKABJYQDMJTNGQ-UHFFFAOYSA-N
• SMILES: O=NN1CCCC1c1cccnc1