Norbinaltorphimine Dihydrochloride Salt

CAS: 113158-34-2

Ref. TR-N661125

Informação sobre produto

• Nome: Norbinaltorphimine Dihydrochloride Salt
• Sinónimos: (4bS,8R,8aS,10aS,11R,14aS,19aR,20bR)-7,12-Bis(cyclopropylmethyl)-5,6,7,8,9,10,11,12,13,14,19a,20b-dodecahydro-4,8:11,15-dimethano-20H-bisbenzofuro[2,3-a:3',2'-i]dipyrido[4,3-b:3',4'-h]carbazole-1,8a,10a,18-tetrol Dihydrochloride, [8R-(4bS*,8α,8aβ,10aα,11β,14aS*,19aα,20bβ)]-7,12-Bis(cyclopropylmethyl)-5,6,7,8,9,10,11,12,13,14,19a,20b-dodecahydro-4,8:11,15-dimethano-20H-bisbenzofuro[2,3-a:3',2'-i]dipyrido[4,3-b:3',4'-h]carbazole-1,8a,10a,18-tetrol Dihydrochloride, N-Demethylbinaltorphimine Dihydrochloride
• CAS: 113158-34-2

Descrição

Applications Norbinaltorphimine Dihydrochloride Salt is a synthetic derivative of Naltrexone (N285750, HCl) and is useful as a κ-opioid antagonist.
References Agmo, A., et al.: Neuropharmacology, 37, 223 (1998); Nagase, H., et al.: Jpn. Kokai Tokkyo Koho. JP 03193782 A 19910823. Aug 23, 1991; Portoghese, P.S., et al.: J. Med. Chem., 31, 836 (1988)

• Marca: TRC

Propriedades químicas

• Peso molecular: 734.708
• Fórmula: C₄₀H₄₅Cl₂N₃O₆
• Cor/forma: Neat
• InChI: InChI=1S/C40H43N3O6.2ClH/c44-25-7-5-21-13-27-39(46)15-23-24-16-40(47)28-14-22-6-8-26(45)34-30(22)38(40,10-12-43(28)18-20-3-4-20)36(49-34)32(24)41-31(23)35-37(39,29(21)33(25)48-35)9-11-42(27)17-19-1-2-19;;/h5-8,19-20,27-28,35-36,41,44-47H,1-4,9-18H2;2*1H/t
• SMILES: Oc1ccc2c3c1O[C@H]1c4[nH]c5c(c4C[C@@]4(O)[C@@H](C2)N(CC2CC2)CC[C@]314)C[C@@]1(O)[C@H]2Cc3ccc(O)c4c3[C@@]1(CCN2CC1CC1)[C@H]5O4