(epsilonR,1R,3aR,4S,7aR)-Octahydro-4-hydroxy-a,a,epsilon,7a-tetramethyl-1H-indene-1-pentanol-d6

CAS: 66774-84-3

Ref. TR-O236457

Informação sobre produto

• Nome: (epsilonR,1R,3aR,4S,7aR)-Octahydro-4-hydroxy-a,a,epsilon,7a-tetramethyl-1H-indene-1-pentanol-d6
• Sinónimos: (1R,3aR,4S,7aR)-1-((R)-6-Hydroxy-6-methylheptan-2-yl)-7a-methyloctahydro-1H-inden-4-ol-d6
• Marca: TRC

Descrição

Applications (εR,1R,3aR,4S,7aR)-Octahydro-4-hydroxy-α,α,ε,7a-tetramethyl-1H-indene-1-pentanol-d6 is an intermediate in synthesizing Calcitriol-d6 (C144502), the biologically active form of vitamin D3. Calcium regulator; vitamin (antirachitic); antihyperparathyroid; antineoplastic; antipsoriatic. (εR,1R,3aR,4S,7aR)-Octahydro-4-hydroxy-α,α,ε,7a-tetramethyl-1H-indene-1-pentanol-d6 is also a labelled analogue of (εR,1R,3aR,4S,7aR)-Octahydro-4-hydroxy-α,α,ε,7a-tetramethyl-1H-indene-1-pentanol (O236455).
References Myrtle, J.F., et al.: J. Biol. Chem., 245, 1190 (1970); Lawson, D.E.M., et al.: Nature, 230, 228 (1971); Norman, A.W., et al.: Science, 173, 51 (1971); Suda, T., et al.: Vitamins, 45, 175 (1972); Muindi, J.R., et al.: Clin. Pharmacol. Ther., 72, 648 (2002)

Propriedades químicas

• Peso molecular: 288.5
• Fórmula: C₁₈H₂₈D₆O₂
• Cor/forma: Neat
• InChI: InChI=1S/C18H34O2/c1-13(7-5-11-17(2,3)20)14-9-10-15-16(19)8-6-12-18(14,15)4/h13-16,19-20H,5-12H2,1-4H3/t13-,14-,15+,16+,18-/m1/s1/i2D3,3D3
• Chave InChI: InChIKey=QDEPNKWUQUKTAM-UHFFFAOYSA-N
• SMILES: CC(=O)Nc1ccc(F)cc1B1OC(C)(C)C(C)(C)O1