Ormetoprim

CAS: 6981-18-6

Ref. TR-O686800

Informação sobre produto

• Nome: Ormetoprim
• Sinónimos: 5-[(4,5-dimethoxy-2-methylphenyl)methyl]pyrimidine-2,4-diamine, 2,4-Diamino-5-(2-methyl-4,5-dimethoxybenzyl)pyrimidine, 2,4-Diamino-5-(3,4-dimethoxy-6-methylbenzyl)pyrimidine, 2,4-Diamino-5-(4,5-dimethoxy-2-methylbenzyl)pyrimidin, 2,4-Diamino-5-(4,5-dimethoxy-2-methylbenzyl)pyrimidine, 2,4-Diamino-5-(6-methylveratryl)pyrimidine, 2,4-Pyrimidinediamine, 5-((4,5-dimethoxy-2-methylphenyl)methyl)-, 5-(2,4,5-Trimethoxybenzyl)Pyrimidine-2,4-Diamine, 5-(4,5-Dimethoxy-2-Methylbenzyl)-2,4-Diaminopyrimidine, 5-(4,5-Dimethoxy-2-Methylbenzyl)Pyrimidine-2,4-Diamine, 5-[(4,5-Dimethoxy-2-methylphenyl)methyl]-2,4-pyrimidinediamine, Nsc 95072, Ormethoprim, Ormetoprima, Ormetoprima [INN-Spanish], Ormetoprime, Ormetoprime [INN-French], Ormetoprimum, Ormetoprimum [INN-Latin], Ormetorprim, Pyrimidine, 2,4-diamino-5-(6-methylveratryl)-, Ro 5-9754, Rofenaid, Unii-M3Efs94984, component of Rofenaid
• CAS: 6981-18-6

Descrição

Stability Hygroscopic
Applications It is a potent and selective inhibitor of bacterial dihydrofolate reductase, the enzyme responsible for the NADPH-dependent reduction of 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate. Antibacterial.This compound is a contaminant of emerging concern (CECs).
References Manius, G.J., et al.: Anal. Profiles Drug Subs., 7, 445 (1978), Roth, B., et al.: J. Med. Chem., 23, 379 (1980), Brogden, R.N., et al.: Drugs, 23, 405 (1982),

• Marca: TRC

Propriedades químicas

• Peso molecular: 274.32
• Fórmula: C₁₄H₁₈N₄O₂
• Cor/forma: Off-White
• InChI: InChI=1S/C14H18N4O2/c1-8-4-11(19-2)12(20-3)6-9(8)5-10-7-17-14(16)18-13(10)15/h4,6-7H,5H2,1-3H3,(H4,15,16,17,18)
• Chave InChI: InChIKey=KEEYRKYKLYARHO-UHFFFAOYSA-N
• SMILES: COc1cc(C)c(Cc2c[nH]c(=N)[nH]c2=N)cc1OC