(S,S)-Oxaliplatin

CAS: 61758-77-8

Ref. TR-O845080

Informação sobre produto

• Nome: (S,S)-Oxaliplatin
• Sinónimos: Platinum, [(1S,2S)-1,2-cyclohexanediamine-kappaN1,kappaN2][ethanedioato(2-)-kappaO1,kappaO2]-, (SP-4-2)-, Platinum, (1,2-cyclohexanediamine-kappaN,kappaN')[ethanedioato(2-)-kappaO1,kappaO2]-, [SP-4-2-[1S-(trans)]]-, Platinum, [(1S,2S)-1,2-cyclohexanediamine-kappaN,kappaN'][ethanedioato(2-)-kappaO1,kappaO2]- (9CI), 1,2-Cyclohexanediamine, platinum complex, (1S-trans)-, [(1S,2S)-1,2-Cyclohexanediamine-kappaN1,kappaN2][ethanedioato(2-)-kappaO1,kappaO2]platinum, NSC 266042, Platinum, (1,2-cyclohexanediamine-N,N')[ethanedioato(2-)-O,O']-, [SP-4-2-(1S-trans)]-, (SP-4-2)-[(1S,2S)-Cyclohexane-1,2-diamine-kappaN,kappaN'][ethanedioato(2-)-kappaO1,kappaO2]platinum, Oxaliplatin Imp. D (EP), Oxaliplatin Related Compound D (USP)

Descrição

Applications The (S,S) Oxaliplatin isomer. Third generation platinum complex. An antitumor agent with activity against colorectal cancer. Cytotoxicity follows the formation of adducts with DNA. Antineoplastic.
References Kidani, Y., et al.: J. Med. Chem., 21, 1315 (1978), Kizu, R., et al.: Cancer Chemother. Pharmacol., 31, 475 (1993), Levi, F., et al.: Eur. J. Cancer, 29A, 1280 (1993), Simpson, D., et al.: Drugs, 63, 2127 (2003),

• Marca: TRC

Propriedades químicas

• Peso molecular: 397.29
• Fórmula: C₈H₁₄N₂O₄Pt
• Cor/forma: White
• InChI: (H,3,4)(H,5,6), InChI=1S/C6H14N2.C2H2O4.Pt/c7-5-3-1-2-4-6(5)8, 3-1(4)2(5)6, , /m0../s1, /q, , /h5-6H,1-4,7-8H2, +2/p-2/t5-,6-
• Chave InChI: InChIKey=ZROHGHOFXNOHSO-USPAICOZSA-L