(2S,3S)-2,3-Oxiranedicarboxylic Acid Monoethyl Ester

CAS: 89886-73-7

Ref. TR-O846925

Informação sobre produto

• Nome: (2S,3S)-2,3-Oxiranedicarboxylic Acid Monoethyl Ester
• Sinónimos: (2S-trans)-2,3-Oxiranedicarboxylic Acid Monoethyl Ester, (2S,3S)-3-(Ethoxycarbonyl)oxirane-2-carboxylic Acid, (2S,3S)-2,3-Oxiranedicarboxylic Acid 2-Ethyl Ester
• Marca: TRC
• Descrição: Applications (2S,3S)-2,3-Oxiranedicarboxylic Acid Monoethyl Ester is used in the synthesis of aza-peptidyl inhibitors of lysosomal asparaginyl endopeptidase, legumain. Also used in the synthesis of irreversible epidermal growth factor receptor inhibitors and probes for cathespins.References Lee, J. et al.: Bioorg. Med. Chem. Lett., 22, 1340 (2012); Carmi, C. et al.: J. Med. Chem., 53, 2038 (2010); Hillaert, U. et al.: Angew. Chem. Int. Ed., 48, 1629 (2009)

Propriedades químicas

• Peso molecular: 160.12
• Fórmula: C₆H₈O₅
• Cor/forma: Colourless
• InChI: InChI=1S/C6H8O5/c1-2-10-6(9)4-3(11-4)5(7)8/h3-4H,2H2,1H3,(H,7,8)/t3-,4-/m0/s1
• Chave InChI: InChIKey=MWMZDXCRDIBPCO-IMJSIDKUSA-N
• SMILES: CCOC(=O)[C@H]1O[C@@H]1C(=O)O