Paclitaxel-13C6

CAS: 33069-62-4

Ref. TR-P132504

Informação sobre produto

• Nome: Paclitaxel-13C6
• Sinónimos: Abraxane-13C6, Genaxol-13C6, Genetaxyl-13C6, OncoGel-13C6, Onxal-13C6, Pacliex-13C6, Taxol-13C6, Yewtaxan-13C6, NSC 125973-13C6
• Marca: TRC
• Descrição: Applications Paclitaxel-13C is the labeled analogue of Paclitaxel (P132500). Paclitaxel is an antineoplastic. Used in the study of structure and function of microtubles into tubulin. Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanced forms of Kaposi's sarcoma. Paclitaxel is a mitotic inhibitor used in cancer chemotherapy.References Letourneau, P.C., et al.: J. Cell Biol., 98, 1355 (1984), Manfredi, J.J., et al.: Pharmacol. Ther., 25, 83 (1984), Danesi, R., et al.: Mol. Pharmacol., 47, 1106 (1995), Markman, M., et al.: Expert. Opin. Pharmacother., 3, 755 (2002), Stone, G.W., et al.: N. Engl. J. Med., 350, 221 (2004),

Propriedades químicas

• Peso molecular: 859.86
• Fórmula: C₄₁₁₃C₆H₅₁NO₁₄
• Cor/forma: Neat
• InChI: InChI=1S/C47H51NO14/c1-25-31(60-43(56)36(52)35(28-16-10-7-11-17-28)48-41(54)29-18-12-8-13-19-29)23-47(57)40(61-42(55)30-20-14-9-15-21-30)38-45(6,32(51)22-33-46(38,24-58-33)62-27(3)50)39(53)37(59-26(2)49)34(25)44(47,4)5/h7-21,31-33,35-38,40,51-52,57H,22-24H2,1-6H3,(H,48,54)/t31-,32-,33+,35+,36-,37+,38+,40-,45+,46-,47+/m0/s1/i9+1,14+1,15+1,20+1,21+1,30+1
• Chave InChI: InChIKey=RCINICONZNJXQF-IEMAKSHKSA-N
• SMILES: CC(=O)O[C@H]1C(=O)[C@]2(C)[C@@H](O)C[C@H]3OC[C@@]3(OC(C)=O)[C@@H]2[C@H](OC(=O)[13c]2[13cH][13cH][13cH][13cH][13cH]2)[C@]2(O)C[C@H](OC(=O)[C@@H](O)[C@H](NC(=O)c3ccccc3)c3ccccc3)C(C)=C1C2(C)C