Pafuramidine

CAS: 186953-56-0

Ref. TR-P133875

Informação sobre produto

• Nome: Pafuramidine
• Sinónimos: 2,5-Bis(4-amidinophenyl)furan-bis-O-methylamidoxime, 4,4'-(2,5-Furandiyl)bis[N-methoxybenzenecarboximidamide], 4,4'-(2,5-Furandiyl)bis[N-methoxybenzenecarboximidamide

Descrição

Applications Pafuramidine is a prodrug of Furamidine (F863600, 2HCl); a diphenylfuran compound belonging to an important class of antimicrobial and antiparasitic agents. Furamidine and its analogues also display antitumor activities and showed antiproliferative activities against various tumor cell lines.
References Lansiaux, A. et al.: Cancer Res., 62, 7219 (2002); Steck E.A. et al.: Exp. Parasitol., 52, 404 (1981); Balzarini, J. et al.: Incest. New Drugs, 1, 103 (1983); Thuita, J.K., et al.: Acta Trop., 108, 6 (2008); Lanteri, C.A., et al.: Mol. Pharmacol., 70, 1585 (2006)

• Marca: TRC

Propriedades químicas

• Peso molecular: 364.4
• Fórmula: C₂₀H₂₀N₄O₃
• Cor/forma: Neat
• InChI: InChI=1S/C20H20N4O3/c1-25-23-19(21)15-7-3-13(4-8-15)17-11-12-18(27-17)14-5-9-16(10-6-14)20(22)24-26-2/h3-12H,1-2H3,(H2,21,23)(H2,22,24)
• Chave InChI: InChIKey=UKOQVLAXCBRRGH-UHFFFAOYSA-N
• SMILES: CON=C(N)c1ccc(-c2ccc(-c3ccc(C(N)=NOC)cc3)o2)cc1