Palbociclib N-Aldehyde

CAS: 2174002-16-3

Ref. TR-P139925

Informação sobre produto

• Nome: Palbociclib N-Aldehyde
• Sinónimos: 4-(6-((6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carbaldehyde
• CAS: 2174002-16-3

Descrição

Applications Palbociclib N-Aldehyde is an intermediate in synthesizing Palbociclib N-β-D-Glucuronide Sodium Salt (P139910), a derivative of Palbociclib (P139900) which is an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.
References Finn, R., et al.: Breast Cancer Res., 11, 5 (2009)

• Marca: TRC

Propriedades químicas

• Peso molecular: 475.54
• Fórmula: C₂₅H₂₉N₇O₃
• Cor/forma: Neat
• InChI: InChI=1S/C25H29N7O3/c1-16-20-14-27-25(28-21-8-7-19(13-26-21)31-11-9-30(15-33)10-12-31)29-23(20)32(18-5-3-4-6-18)24(35)22(16)17(2)34/h7-8,13-15,18H,3-6,9-12H2,1-2H3,(H,26,27,28,29)
• Chave InChI: InChIKey=JNHDLNXNYPLBMJ-UHFFFAOYSA-N
• SMILES: OCc1nccs1