α-Phenyl-α-[3-(phenyl-2-pyridinylmethylene)-2,4-cyclopentadien-1-yl]-2-pyridinemethanol (E/Z mixture)

CAS: 2026-58-6

Ref. TR-P321585

Informação sobre produto

• Nome: α-Phenyl-α-[3-(phenyl-2-pyridinylmethylene)-2,4-cyclopentadien-1-yl]-2-pyridinemethanol (E/Z mixture)
• Sinónimos: α-Phenyl-α-[3-(α-2-pyridylbenzylidene)-1,4-cyclopentadien-1-yl]-2-pyridinemethanol
• Marca: TRC
• Descrição: Applications α-Phenyl-α-[3-(phenyl-2-pyridinylmethylene)-2,4-cyclopentadien-1-yl]-2-pyridinemethanol is an intermediate in the synthesis of Norbormide (N661150), a rodenticide that acts as a vasoconstrictor and calcium channel blocker, but is selectively toxic to rats and has relatively low toxicity to other species, due to a species specific action of opening the permeability transition pores in rat mitochondria.References Rennison, D., et al.: Bioorg. Med. Chem. 15, 2963 (2007)

Propriedades químicas

• Peso molecular: 414.5
• Fórmula: C₂₉H₂₂N₂O
• Cor/forma: Neat
• InChI: InChI=1S/C29H22N2O/c32-29(24-13-5-2-6-14-24,27-16-8-10-20-31-27)25-18-17-23(21-25)28(22-11-3-1-4-12-22)26-15-7-9-19-30-26/h1-21,32H
• Chave InChI: InChIKey=KKEROSKQAHUOAE-NFFVHWSESA-N
• SMILES: OC(C1=C/C(=C(/c2ccccc2)c2ccccn2)C=C1)(c1ccccc1)c1ccccn1