rac-Pinocembrin

CAS: 68745-38-0

Ref. TR-P468495

Informação sobre produto

• Nome: rac-Pinocembrin
• Sinónimos: 5,7-dihydroxy-2-phenyl-2,3-dihydrochromen-4-one, 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-phenyl-, 5,7-Dihydroxy-2-phenyl-2,3-dihydro-4H-chromen-4-on, 5,7-Dihydroxy-2-Phenyl-Chroman-3-One, Pinocembrin, 5,7-Dihydroxy-2-phényl-2,3-dihydro-4H-chromén-4-one

Descrição

Applications Pinocembrin is a flavanoid with antioxidant activity found in damiana, honey, and propolis. Recent studies show that Pinocembrin maybe be a therapeutic option in reducing cerebral ischemia/reperfusion injury as a result of its anti-oxidative and anti-apoptotic effects. Pinocembrin displayed neuroprotective effects in glutamate injury model partly by inhibiting p53 expression causing a lower Bax-Bcl-2 ratio and by inhibiting the release of cytochrome c.
References Zhao, J. et al.: J. Ethnopharmacol., 120, 387 (2008); Liu, R. et al.: Brain Res., 1216, 104 (2008); Gao, M. et al.: Eur. J. Pharmacol., 591, 73 (2008);

• Marca: TRC

Propriedades químicas

• Peso molecular: 256.25
• Fórmula: C₁₅H₁₂O₄
• Cor/forma: Off-White
• InChI: InChI=1S/C15H12O4/c16-10-6-11(17)15-12(18)8-13(19-14(15)7-10)9-4-2-1-3-5-9/h1-7,13,16-17H,8H2
• Chave InChI: InChIKey=URFCJEUYXNAHFI-UHFFFAOYSA-N
• SMILES: O=C1CC(c2ccccc2)Oc2cc(O)cc(O)c21