Pregnanetriol-d4

CAS: 1098-45-9

Ref. TR-P705162

Informação sobre produto

• Nome: Pregnanetriol-d4
• Sinónimos: (3a,5ß,20S)-Pregnane-3,17,20-triol-d4, 5ß-Pregnane-3a,17,20a-triol-d4, 3a,17a,20a-Trihydroxy-5ß-pregnane, 5ß-Pregnane-3a,17a,20a-triol-d4, NSC 52760-d4, 5β-Pregnane-3α,17α,20α-triol, Pregnane-3,17,20-triol, (3α,5β,20S)-, 3α,17α,20α-Trihydroxy-5β-pregnane, (3α,5β,20S)-Pregnane-3,17,20-triol, 5β-Pregnane-3α,17,20α-triol

Descrição

Applications Labelled Pregnanetriol, a steroid present at elevated levels in the urine of patients with congenital adrenal hyperplasma. During treatment with cortisol replacement, elevated urine Pregnanetriol levels indicate insufficient dosage of cortisol. Pregnanetriol is also one of the urinary marker for adrenal incidentaloma. Pregnanetriol is a metabolite of Androstenedione (A637550).
References Kinoshita, K. et al.: J. Clin. Endocrinol., 26, 1219 (1966); Kotlowska, A. et al.: Clin. Biochem., 42, 448 (2009); Wang, J. et al.: Zhipu Xue., 25, 201 (2004);

• Marca: TRC

Propriedades químicas

• Peso molecular: 340.53
• Fórmula: C₂₁H₃₂D₄O₃
• Cor/forma: Neat
• InChI: InChI=1S/C21H36O3/c1-13(22)21(24)11-8-18-16-5-4-14-12-15(23)6-9-19(14,2)17(16)7-10-20(18,21)3/h13-18,22-24H,4-12H2,1-3H3/t13?,14-,15-,16-,17+,18+,19+,20+,21+/m1/s1/i1D3,13D
• Chave InChI: InChIKey=SCPADBBISMMJAW-GVNXEIMNSA-N
• SMILES: [2H]C([2H])([2H])C([2H])(O)[C@@]1(O)CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@@]21C