δ4-Pregnen-20α-ol-3-one

CAS: 145-14-2

Ref. TR-P712215

Informação sobre produto

• Nome: δ4-Pregnen-20α-ol-3-one
• Sinónimos: Progesterone EP Impurity B, (20R)-20-hydroxypregn-4-en-3-one, (20S)-20-Hydroxypregn-4-en-3-on, (20S)-20-Hydroxypregn-4-en-3-one, (20S)-20-hidroxipregn-4-en-3-ona, (20S)-20-hydroxypregn-4-ene-3-one, (8S,9S,10R,13S,14S,17S)-17-(1-hydroxyethyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one, (8xi,9xi,14xi,17xi,20S)-20-hydroxypregn-4-en-3-one, 20(S)-Hydroxyprogesterone, 20-Hydroxypregn-4-En-3-One, 20-alpha-Dihydroprogesterone, 20-alpha-Hydroxydihydroprogesterone, 20-alpha-Hydroxyprogesterone, 20-alpha-Progerol, 20alpha-Dihydroprogesterone, 20alpha-Dihydroprognenolone, 20alpha-Hydroxydihydroprogesterone, 20alpha-Hydroxypreg-4-en-3-one, 20alpha-Hydroxypregnen-2-one, 20alpha-Progerol, 20α-Dihydroprogesterone, 20α-Hydroxy-4-pregnen-3-one, 20α-Hydroxy-Δ4-pregnen-3-one, 20α-Hydroxy-Δ⁴-pregnen-3-one, 20α-Hydroxydihydroprogesterone, 20α-Hydroxypregn-4-en-3-one, 20α-Hydroxyprogesterone, 20α-Progerol, 4-Pregnen-3-one-20α-ol, Brn 2220567, Dihydrogesterone, Dihydroprogesterone, Nsc 68630, Pregn-4-en-20α-ol-3-one, Pregn-4-en-3-one, 20-alpha-hydroxy-, Pregn-4-en-3-one, 20-hydroxy-, (20S)-, Pregn-4-en-3-one, 20-hydroxy-, (20S)- (9CI), Pregn-4-en-3-one, 20alpha-hydroxy- (8CI), Pregn-4-en-3-one, 20α-hydroxy-, Pregn-4-ene-20α-ol-3-one, Progesterol-20-alpha, Progesterol-20α, Δ4-Pregnen-20α-ol-3-one, Δ4-Pregnene-20α-ol-3-one, Δ⁴-Pregnen-20α-ol-3-one, Δ⁴-Pregnene-20α-ol-3-one, 4-08-00-01018 (Beilstein Handbook Reference)

Descrição

Impurity Progesterone EP Impurity B
Applications Δ4-Pregnen-20α-ol-3-one (Progesterone EP Impurity B) is the main metabolite of Progesterone (P755900). Studies shows regulation of estrogen receptor levels in breast cancer by Δ4-Pregnen-20α-ol-3-one and other progesterone metabolites.
References Zhang, L. et al.: Yaoz. Xueb., 39, 613 (2004); Pawlak, K.J. et al.: J. Steroid. Biochem. Mol. Biol., 107, 172 (2007);

• Marca: TRC

Propriedades químicas

• Peso molecular: 316.48
• Fórmula: C₂₁H₃₂O₂
• Cor/forma: Off White Solid
• InChI: InChI=1S/C21H32O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12-13,16-19,22H,4-11H2,1-3H3/t13-,16-,17+,18-,19-,20-,21+/m0/s1
• Chave InChI: InChIKey=RWBRUCCWZPSBFC-RXRZZTMXSA-N
• SMILES: C[C@H](O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C