L-Propoxyphene-d5 Hydrochloride

CAS: 1276197-49-9

Ref. TR-P831512

Informação sobre produto

• Nome: L-Propoxyphene-d5 Hydrochloride
• Sinónimos: [R-(R*,S*)]-α-[2-(Dimethylamino)-1-methylethyl]-α-phenyl-benzeneethanol Propanoate (Ester) Hydrochloride-d5, (-)-4-(Dimethylamino)-3-methyl-1,2-diphenyl-2-butanol Propionate Hydrochloride-d5, Levopropoxyphene Hydrochloride-d5, α-l-Propoxyphene Hydrochloride-d5

Descrição

Applications L-Propoxyphene-d5 Hydrochloride is the isotope labelled analog and L-isomer of Propoxyphene Hydrochloride (P831500); a controlled substance (opiate) and analgesic (narcotic). The α-DL-and D-diastereoisomers possess marked analgesic activity in contrast to the β-diastereoisomers which are substantially inactive. Oral administration of L-Propoxyphene Hydrochloride enhances the analgesic activity of D-Propoxyphene Hydrochloride.
References Goldenthal, E.I., et al.: Toxicol. Appl. Pharmacol., 18, 185 (1971); McEwan, B., et al.: Anal. Profiles Drug Subs., 1, 301 (1972); Murphy, P.J., et al.: J. Pharmacol. Exp. Ther., 199, 415 (1976)

• Marca: TRC

Propriedades químicas

• Peso molecular: 380.96
• Fórmula: C₂₂H₂₅D₅ClNO₂
• Cor/forma: Neat
• InChI: InChI=1S/C15H12O2.C2H6/c1-9-6-7-12-13(8-9)15(17)11-5-3-2-4-10(11)14(12)16;1-2/h2-8,10-11H,1H3;1-2H3
• Chave InChI: InChIKey=UPWWMRQTWKAIAM-UHFFFAOYSA-N
• SMILES: CC.Cc1ccc2c(c1)C(=O)C1C=CC=CC1C2=O