Prucalopride Succinate

CAS: 179474-85-2

Ref. TR-P838950

Informação sobre produto

• Nome: Prucalopride Succinate
• Sinónimos: Butanedioic acid, compd. with 4-amino-5-chloro-2,3-dihydro-N-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzofurancarboxamide (1:1), 7-Benzofurancarboxamide, 4-amino-5-chloro-2,3-dihydro-N-[1-(3-methoxypropyl)-4-piperidinyl]-, butanedioate (1:1) (9CI), R 108512, Resolor, Resotran, Prucalopride INTERMEDIATES, Prucalopride succinate
• CAS: 179474-85-2

Descrição

Applications Prucalopride is a selective 5-HT4 receptor agonist used effective for chronic constipation, but is not currently approved in the U.S. Prucalopride is approved for the treatment of chronic constipation in Europe.
References Shah, N., et al.: Am. J. Gastroenterol., 103, 1746 (2008), McKinnell, R., et al.: J. Med. Chem., 52, 5330 (2009), Shah, N., et al.: Am. J. Gastroenterol., 103, 1746 (2008),

• Marca: TRC

Propriedades químicas

• Peso molecular: 485.96
• Fórmula: C₁₈H₂₆N₃O₃Cl•CH₆O₄
• Cor/forma: Neat
• InChI: 5-3(6)1-2-4(7)8/h11-12H,2-10,20H2,1H3,(H,21,23), 1-2H2,(H,5,6)(H,7,8), InChI=1S/C18H26ClN3O3.C4H6O4/c1-24-9-2-6-22-7-3-12(4-8-22)21-18(23)14-11-15(19)16(20)13-5-10-25-17(13)14
• Chave InChI: InChIKey=QZRSNVSQLGRAID-UHFFFAOYSA-N
• SMILES: COCCCN1CCC(NC(=O)c2cc(Cl)c(N)c3c2OCC3)CC1.O=C(O)CCC(=O)O