Simvastatin Hydroxy Acid Sodium Salt

CAS: 101314-97-0

Ref. TR-S485050

Informação sobre produto

• Nome: Simvastatin Hydroxy Acid Sodium Salt
• Sinónimos: Simvastatin Imp. A (EP), (3R,5R)-7-[(1S,2S,6R,8S,8aR)-8-[(2,2-Dimethylbutanoyl)oxy]-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic Acid Sodium Salt, Simvastatin Imp. A (EP) as Sodium Salt, Tenivastatin Sodium Salt, Simvastatin Impurity A as Sodium Salt
• CAS: 101314-97-0

Descrição

Impurity Simvastatin EP Impurity A
Applications Simvastatin Hydroxy Acid Sodium Salt is a metabolite of Simvastatin (S485000), a synthetic derivative of a fermentation product of Aspergillus terreus. A competitive inhibitor of HMG-CoA reductase. A synthetic analog of Lovastatin. Antilipemic. Simvastatin, the drug, is sold under the trade name Zocor.
References Hoffman, W.F., et al.: J. Med. Chem., 29, 849 (1986); Mol, M.J., et al.: Lancet, 2, 936 (1986)

• Marca: TRC

Propriedades químicas

• Peso molecular: 458.56
• Fórmula: C₂₅H₃₉NaO₆
• Cor/forma: Neat
• InChI: /h7-8,11,15-16,18-21,23,26-27H,6,9-10,12-14H2,1-5H3,(H,28,29), /q, InChI=1S/C25H40O6.Na/c1-6-25(4,5)24(30)31-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-18(26)13-19(27)14-22(28)29, /m0./s1, +1/p-1/t15-,16-,18+,19+,20-,21-,23-
• Chave InChI: InChIKey=RLWRROYWKHUVKF-OKDJMAGBSA-M
• SMILES: CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(=O)O[Na])[C@H]21