SN-38 Glucuronide

CAS: 121080-63-5

Ref. TR-S589980

Informação sobre produto

• Nome: SN-38 Glucuronide
• Sinónimos: β-D-Glucopyranosiduronic acid, (4S)-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl, β-D-Glucopyranosiduronic acid, 4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl, (S)-, (4S)-4,11-Diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl β-D-glucopyranosiduronic acid, SN 38G, 10-Hydroxy-7-ethylcamptothecin 10-β-D-glucuronide, 7-Ethyl-10-hydroxy-20(S)-camptothecin 10-β-D-glucuronide, 7-Ethyl-10-hydroxycamptothecin 10-β-D-glucuronide, (4S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione 9-(β-D-glucopyranosiduronide)
• Marca: TRC
• Descrição: Applications A metabolite of IrinotecanReferences Fujita, K., et al.: Biol. Pharm. Bull., 31, 2137 (2008), Sandanaraj, E., et al.: Pharmacogen. J., 8, 174 (2008), Chen, K., et al.: Chem. Biol., 15, 1277 (2008), Prijovich, Z., et al.: Mol. Canc. Ther., 8, 940 (2009),

Propriedades químicas

• Peso molecular: 568.53
• Fórmula: C₂₈H₂₈N₂O₁₁
• Cor/forma: White To Yellow
• InChI: InChI=1S/C28H28N2O11/c1-3-12-13-7-11(40-26-22(33)20(31)21(32)23(41-26)25(35)36)5-6-17(13)29-19-14(12)9-30-18(19)8-16-15(24(30)34)10-39-27(37)28(16,38)4-2/h5-8,20-23,26,31-33,38H,3-4,9-10H2,1-2H3,(H,35,36)/t20-,21-,22+,23-,26+,28-/m0/s1
• Chave InChI: InChIKey=SSJQVDUAKDRWTA-CAYKMONMSA-N
• SMILES: CCc1c2c(nc3ccc(O[C@@H]4O[C@H](C(=O)O)[C@@H](O)[C@H](O)[C@H]4O)cc13)-c1cc3c(c(=O)n1C2)COC(=O)[C@]3(O)CC