Taltirelin Trifluoroacetic Acid Salt

CAS: 103300-74-9

Ref. TR-T005650

Informação sobre produto

• Nome: Taltirelin Trifluoroacetic Acid Salt
• Sinónimos: (4S)-Hexahydro-1-methyl-2,6-dioxo-4-pyrimidinecarbonyl-L-histidyl-L-prolinamide Trifluoroacetic Acid, ‡(S)-N-(1Methyl-4,5-dihydroorotyl)-L-histidyl-L-prolinamide Trifluoroacetic Acid, TA 0910 Trifluoroacetic Acid, (4S)-Hexahydro-1-methyl-2,6-dioxo-4-pyrimidinecarbonyl-<span class="text-smallcaps">L</smallcap>-histidyl-<smallcap>L</span>-prolinamide, (4S)-N-[(2S)-1-[(2S)-2-Carbamoylpyrrolidin-1-yl]-3-(3H-imidazol-4-yl)-1-oxopropan-2-yl]-1-methyl-2,6-dioxo-1,3-diazinane-4-carboxamide, 2,6-dioxo-4-pyrimidinecarbonyl-L-histidyl-, <span class="text-smallcaps">L</smallcap>-Prolinamide, (4S)-hexahydro-1-methyl-2,6-dioxo-4-pyrimidinecarbonyl-<smallcap>L</span>-histidyl-, <span class="text-smallcaps">L</smallcap>-Prolinamide, N-[(hexahydro-1-methyl-2,6-dioxo-4-pyrimidinyl)carbonyl]-<smallcap>L</span>-histidyl-, (S)-, Ceredist, L-Prolinamide, N-[(hexahydro-1-methyl-2,6-dioxo-4-pyrimidinyl)carbonyl]-L-histidyl-, (S)-, L-Prolinamide, N-[[(4S)-hexahydro-1-methyl-2,6-dioxo-4-pyrimidinyl]carbonyl]-L-histidyl- (9CI), L-Prolinamide,(4S)-hexahydro-1-methyl-, N-{[(4S)-1-methyl-2,6-dioxohexahydropyrimidin-4-yl]carbonyl}-L-histidyl-L-prolinamide, Ta 0910
• CAS: 103300-74-9

Descrição

Stability Hygroscopic
Applications Analog of thyrotropin releasing hormone TRH, with pronounced CNS activity. Used in the treatment of spinocerebellar degeneration.
References Yamamura, M., et al.: Jpn. J. Pharmacol., 53, 451 (1990), Iwasaki, Y., et al.: Neurol. Res., 19, 613 (1997), Kinoshita, K., et al.: CNS Drug Rev., 4, 25 (1998), Morikawa, S., et al.: J. Pharm. Biomed. Anal., 16, 1267 (1998),

• Marca: TRC

Propriedades químicas

• Peso molecular: 519.43
• Fórmula: C₁₉H₂₄F₃N₇O₇
• Cor/forma: Neat
• InChI: InChI=1S/C17H23N7O5.C2HF3O2/c1-23-13(25)6-10(22-17(23)29)15(27)21-11(5-9-7-19-8-20-9)16(28)24-4-2-3-12(24)14(18)26;3-2(4,5)1(6)7/h7-8,10-12H,2-6H2,1H3,(H2,18,26)(H,19,20)(H,21,27)(H,22,29);(H,6,7)/t10-,11-,12-;/m0./s1
• Chave InChI: InChIKey=MPHHNZYPQHGMFE-LFELFHSZSA-N
• SMILES: CN1C(=O)C[C@@H](C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N2CCC[C@H]2C(N)=O)NC1=O.O=C(O)C(F)(F)F