(1S,2R)-Tapentadol Hydrochloride

CAS: 1282502-22-0

Ref. TR-T007225

Informação sobre produto

• Nome: (1S,2R)-Tapentadol Hydrochloride
• Sinónimos: Phenol, 3-[(1S,2R)-3-(dimethylamino)-1-ethyl-2-methylpropyl]-, hydrochloride (1:1), 3-[(1S,2R)-3-(Dimethylamino)-1-ethyl-2-methylpropyl]phenol hydrochloride, 3-[(2R,3S)-1-(Dimethylamino)-2-methylpentan-3-yl]phenol hydrochloride

Descrição

Applications (1S,2R)-Tapentadol is the (1S,2R)-isomer of Tapentadol (T007200, HCl); a novel, centrally acting oral analgesic with a dual mode of action that has demonstrated efficacy in preclinical and clinical models of pain relief.
References Znaleziona, J., et al.: J. Pharmaceut. Biomed., 105, 10 (2015); Boxenbaum, H., et al.: J. Pharm. Sci., 2, 47 (1999); Boase, S., et al.: Br. J. Clin. Pharmacol., 54, 493 (2002); Armstrong, S., et al.: Psychosomatics, 44, 515 (2003); Bjornsson, T., et al.: Drug Metab. Dispos., 31, 815 ( 2003)

• Marca: TRC

Propriedades químicas

• Peso molecular: 257.80
• Fórmula: C₁₄H₂₃NO·ClH
• Cor/forma: Neat
• InChI: InChI=1S/C14H23NO.ClH/c1-5-14(11(2)10-15(3)4)12-7-6-8-13(16)9-12;/h6-9,11,14,16H,5,10H2,1-4H3;1H/t11-,14-;/m0./s1
• Chave InChI: InChIKey=ZELFLGGRLLOERW-XCBLFTOQSA-N
• SMILES: CC[C@H](c1cccc(O)c1)[C@@H](C)CN(C)C.Cl