Tenivastatin Calcium Hydrate

CAS: 530112-57-3

Ref. TR-T018425

Informação sobre produto

• Nome: Tenivastatin Calcium Hydrate
• Sinónimos: Tenivastatin calcium, Tenivastatin calcium monohydrate, Calcium (3R,5R)-7-{(1S,2S,6R,8S,8aR)-8-[(2,2-dimethylbutanoyl)oxy]-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl}-3,5-dihydroxyheptanoate (1:2) monohydrate
• CAS: 530112-57-3

Descrição

Applications Tenivastatin Calcium is derived from Simvastatin (S485000), which is a synthetic derivative of a fermentation product of Aspergillus terreus. A competitive inhibitor of HMG-CoA reductase. A synthetic analog of Lovastatin. Antilipemic. Simvastatin, the drug, is sold under the trade name Zocor.
References Hoffman, W.F., et al.: J. Med. Chem., 29, 849 (1986), Mol, M.J., et al.: Lancet, 2, 936 (1986)

• Marca: TRC

Propriedades químicas

• Peso molecular: 929.24
• Fórmula: C₂₅H₄₀O₆(Ca)•x(HO)
• Cor/forma: Neat
• InChI: , /h2*7-8,11,15-16,18-21,23,26-27H,6,9-10,12-14H2,1-5H3,(H,28,29), /p-2/t2*15-,16-,18+,19+,20-,21-,23-, InChI=1S/2C25H40O6.Ca.H2O/c2*1-6-25(4,5)24(30)31-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-18(26)13-19(27)14-22(28)29, , 1H2/q, , , /m00../s1, +2
• Chave InChI: InChIKey=OAGNASNTPWMGKY-OKDJMAGBSA-N
• SMILES: CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(=O)O)[C@H]21.O