Terlipressin Diacetate Salt

CAS: 1884420-36-3

Ref. TR-T115800

Informação sobre produto

• Nome: Terlipressin Diacetate Salt
• Sinónimos: 1-Triglycyl-8-lysine Vasopressin Diacetate Salt, 130: PN: WO2010033207 SEQID: 171 claimed protein Diacetate Salt, Glycylpressin Diacetate Salt, Glypressin Diacetate Salt, Na-Gly-Gly-Gly-8-Lys-vasopressin Diacetate Salt, Na-Glycyl-glycyl-glycyl-[8-lysine]-vasopressin Diacetate Salt, Na-Glycyl-glycyl-glycyl-lysine-vasopressin Diacetate Salt, Na-Glycylglycylglycyl-vasopressin Diacetate Salt, Remestyp Diacetate Salt, Triglycyl-8-lysine-vasopressin Diacetate Salt, [N-a-Triglycyl-8-lysine]-vasopressin Diacetate Salt

Descrição

Applications Terlipressin is an analogue of vasopressin used as a vasoactive drug in the management of hypotension. Terlipressin is used norepinephrine-resistant septic shock and hepatorenal syndrome. Terlipressin is also used in the treatment of acute variceal bleeding.
References Uriz, J. et al.: J. Heptol., 33, 43 (2000); O'Brien, A. et al.: Lancet, 359, 1209 (2002); Burroughs, A.K. et al.: Digestion, 59, 26 (1998); Villanueva, C. et al.: Am. J. Gastroenterol., 100, 624 (2005);

• Marca: TRC

Propriedades químicas

• Peso molecular: 1347.48
• Fórmula: C₅₆H₈₂N₁₆O₁₉S₂
• Cor/forma: Off White Solid
• InChI: InChI=1S/C52H74N16O15S2.C2H4O2/c53-17-5-4-9-31(45(76)60-23-41(57)72)63-51(82)38-10-6-18-68(38)52(83)37-27-85-84-26-36(61-44(75)25-59-43(74)24-58-42(73)22-54)50(81)65-34(20-29-11-13-30(69)14-12-29)48(79)64-33(19-28-7-2-1-3-8-28)47(78)62-32(15-16-39(55)70)46(77)66-35(21-40(56)71)49(80)67-37;1-2(3)4/h1-3,7-8,11-14,31-38,69H,4-6,9-10,15-27,53-54H2,(H2,55,70)(H2,56,71)(H2,57,72)(H,58,73)(H,59,74)(H,60,76)(H,61,75)(H,62,78)(H,63,82)(H,64,79)(H,65,81)(H,66,77)(H,67,80);1H3,(H,3,4)/t31-,32-,33+,34-,35-,36-,37-,38-;/m0./s1
• Chave InChI: InChIKey=BYDVFOPTAIPAGA-XLCYGNDGSA-N
• SMILES: CC(=O)O.NCCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CSSC[C@H](NC(=O)CNC(=O)CNC(=O)CN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@H](Cc2ccccc2)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1)C(=O)NCC(N)=O