1-(6,7,9,10-Tetrahydro-6,10-methano-8H-pyrazino[2,3-h][3]benzazepin-8-yl)ethanone

CAS: 1213781-59-9

Ref. TR-T310085

Informação sobre produto

• Nome: 1-(6,7,9,10-Tetrahydro-6,10-methano-8H-pyrazino[2,3-h][3]benzazepin-8-yl)ethanone
• Sinónimos: N-Acetyl Varenicline, 1-((6R,10S)-9,10-Dihydro-6H-6,10-methanoazepino[4,5-g]quinoxalin-8(7H)-yl)ethanone
• Marca: TRC
• Descrição: Applications 1-(6,7,9,10-Tetrahydro-6,10-methano-8H-pyrazino[2,3-h][3]benzazepin-8-yl)ethanone is related to its parent compound N-Formyl Varenicline (F701650), which is a metabolite of Varenicline and metabolite M5. Also, it is derived from Varenicline Tartrate (V098490), which is a nicotinic α4β2 acetylcholine receptor partial agonist and used to aid in smoking cessation (1,2,3,4).References Dow, J., et al.: Drug Metab. Dispos., 22, 738 (1994), Toide, K., et al.: Biochem. Pharmacol., 67, 1269 (2004), Coe, J., et al.: J. Med. Chem., 48, 3474 (2005), Doll, R., et al.: Br. J. Cancer, 92, 426 (2005)

Propriedades químicas

• Peso molecular: 253.299
• Fórmula: C₁₅H₁₅N₃O
• Cor/forma: Neat
• InChI: InChI=1S/C15H15N3O/c1-9(19)18-7-10-4-11(8-18)13-6-15-14(5-12(10)13)16-2-3-17-15/h2-3,5-6,10-11H,4,7-8H2,1H3
• Chave InChI: InChIKey=YMNGQMBVFORKEO-UHFFFAOYSA-N
• SMILES: CC(=O)N1CC2CC(C1)c1cc3nccnc3cc12