Trametinib (DMSO Solvate)

CAS: 1187431-43-1

Ref. TR-T314310

Informação sobre produto

• Nome: Trametinib (DMSO Solvate)
• Sinónimos: Acetamide, N-[3-[3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]-, compd. with 1,1'-sulfinylbis[methane] (1:1), GSK 1120212B, Trametinib dimethyl sulfoxide, GSK 1120212B, Acetamide, N-[3-[3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]-, compd. with 1,1′-sulfinylbis[methane] (1:1), Gsk 1120212B, Trametinib DMSO
• CAS: 1187431-43-1

Descrição

Applications Trametinib (DMSO Solvate) is a highly potent and selective MEK inhibitor with significant antitumor activity.
References Abe, H., et al.: ACS Med. Chem. Lett., 2, 320 (2011)

• Marca: TRC

Propriedades químicas

• Peso molecular: 693.53
• Fórmula: C₂₈H₂₉FIN₅O₅S
• Cor/forma: White
• InChI: InChI=1S/C26H23FIN5O4.C2H6OS/c1-13-22-21(23(31(3)24(13)35)30-20-10-7-15(28)11-19(20)27)25(36)33(17-8-9-17)26(37)32(22)18-6-4-5-16(12-18)29-14(2)34;1-4(2)3/h4-7,10-12,17,30H,8-9H2,1-3H3,(H,29,34);1-2H3
• Chave InChI: InChIKey=OQUFJVRYDFIQBW-UHFFFAOYSA-N
• SMILES: CC(=O)Nc1cccc(-n2c(=O)n(C3CC3)c(=O)c3c(Nc4ccc(I)cc4F)n(C)c(=O)c(C)c32)c1.CS(C)=O