Timolol Maleate

CAS: 26921-17-5

Ref. TR-T443710

Informação sobre produto

• Nome: Timolol Maleate
• Sinónimos: 2-Propanol, 1-[(1,1-dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-, (2S)-, (2Z)-2-butenedioate (1:1), 2-Propanol, 1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]-, (-)-, maleate (1:1) (salt) (8CI), 2-Propanol, 1-[(1,1-dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-, (2S)-, (2Z)-2-butenedioate (1:1) (salt) (9CI), 2-Propanol, 1-[(1,1-dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-, (S)-, (Z)-2-butenedioate (1:1) (salt), 1,2,5-Thiadiazole, 2-propanol deriv., (S)-(-)-Timolol maleate, (S)-Timolol hydrogen maleate, (S)-Timolol maleate, Aquanil, Betim, Betime, Blocadren, Blocanol, Istalol, L-Timolol maleate, MK 950, Optimol, Proflax, Rysmon TG, Temserin, Tenopt, Timabak, Timacar, Timacor, Timolet, Timolol LA, Timolol hydrogen maleate, Timomann, Timoptic, Timoptol, Timoptol XE, Timorom, WP 934, l-Timolol maleate, (-)-Timolol maleate, (2R)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol (2Z)-but-2-enedioate (salt), (2R)-1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol, (2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol (2Z)-but-2-enedioate (salt), (S)-[1-(1,1dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-2-propanol maleate, 1,2,5-Thiadiazole, 2-propanol deriv., 2-Propanol, 1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]-, (-)-, maleate (1:1) (salt), 2-Propanol, 1-[(1,1-dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-, (2S)-, (2Z)-2-butenedioate (1:1), 2-Propanol, 1-[(1,1-dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-, (2S)-, (2Z)-2-butenedioate (1:1) (salt), 2-Propanol, 1-[(1,1-dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-, (S)-, (Z)-2-butenedioate (1:1) (salt), <span class="text-smallcaps">L</span>-Timolol maleate, Apimol, But-2-Enedioic Acid, Isralol, Mk 950, Ocumol, Ophtamolol, Timoftol, Timohexal, Timolast, Timoptol-LA, Wp 934

Descrição

Applications Antihypertensive; antiarrhythmic (class II); antianginal; antiglaucoma agent.
References Wasson, et al.: J. Med. Chem., 15, 651 (1972), Franciosa, et al.: Clin. Pharmacol. Ther., 13, 138 (1972), Heel, R.C., et al.: Drugs, 17, 38 (1979), Rofman, B.A., et al.: Hypertension, 2, 643 (1980), Mazzo, D.J., et al.: Anal. Profiles Drug Subs., 16, 641 (1987),

• Marca: TRC

Propriedades químicas

• Peso molecular: 432.49
• Fórmula: C₁₃H₂₄N₄O₃S·C₄H₄O₄
• Cor/forma: White
• InChI: InChI=1S/C13H24N4O3S.C4H4O4/c1-13(2,3)14-8-10(18)9-20-12-11(15-21-16-12)17-4-6-19-7-5-17;5-3(6)1-2-4(7)8/h10,14,18H,4-9H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-/t10-;/m0./s1
• Chave InChI: InChIKey=WLRMANUAADYWEA-NWASOUNVSA-N
• SMILES: CC(C)(C)NC[C@H](O)COc1nsnc1N1CCOCC1.O=C(O)/C=C\C(=O)O