Tiospirone Hydrochloride

CAS: 87691-92-7

Ref. TR-T444810

Informação sobre produto

• Nome: Tiospirone Hydrochloride
• Sinónimos: 8-[4-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione Hydrochloride, BMY 13859, BMY 13859-1, MJ 13859-1, Tiaspirone Hydrochloride, 8-Azaspiro[4.5]decane-7,9-dione, 8-[4-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]butyl]-, hydrochloride (1:1), 8-Azaspiro[4.5]decane-7,9-dione, 8-[4-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]butyl]-, monohydrochloride, 8-{4-[4-(1,2-Benzothiazol-3-Yl)Piperazin-1-Yl]Butyl}-8-Azaspiro[4.5]Decane-1,4-Dione Hydrochloride (1:1), 8-{4-[4-(1,2-Benzothiazol-3-Yl)Piperazin-1-Yl]Butyl}-8-Azaspiro[4.5]Decane-7,9-Dione Hydrochloride (1:1), Bmy 13859-1, Bmy-13859, MJ-13859(free base), Mj 13859-1, Mj-138591, Tiaspirone hydrochloride, Tiospirone hydrochloride
• CAS: 87691-92-7

Descrição

Applications Tiospirone is an atypical antipsychotic agent and used in the treatment of schizophrenia (1,2,3,). Tiospirone acts as a 5-HT1A receptor partial agonist, 5-HT2A, 5-HT2C, and 5-HT7 receptor inverse agonist, and D2, D4, and α1-adrenergic receptor antagonist.
References (1) Rauly-Lestienne, I. et al.: Naun. Schmeid. Arch. Pharmacol., 376, 93 (2007) (2) Weiner, D.M. et al.: J. Pharmacol. Exp. Therap., 299, 268 (2001) (3) White, F.J. et al.: Neuropharmacology, 25, 995 (1986)

• Marca: TRC

Propriedades químicas

• Peso molecular: 477.06
• Fórmula: C₂₄H₃₃ClN₄O₂S
• Cor/forma: White Solid
• InChI: InChI=1S/C24H32N4O2S.ClH/c29-21-17-24(9-3-4-10-24)18-22(30)28(21)12-6-5-11-26-13-15-27(16-14-26)23-19-7-1-2-8-20(19)31-25-23;/h1-2,7-8H,3-6,9-18H2;1H
• Chave InChI: InChIKey=RYAWYTKDKQCORF-UHFFFAOYSA-N
• SMILES: Cl.O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(c2nsc3ccccc23)CC1